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pLIVE Vector - 20 ug

pLIVE Vector – 20 ug

A vector system designed to achieve long term expression in the livers of laboratory mice

SKU MIR 5420 Category

$564.00

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Description

  • Sustained Gene Expression – Achieve long term liver gene expression in the mouse liver through 8 months post-injection
  • Versatile Platform – Available with positive control vectors expressing either LacZ or SEAP

Maps

 

 

Sequences

The pLIVE® Vector: DOWNLOAD PDF (PDF)

 

 

The Promoter in the pLIVE® Vector Outperforms the CMV Promoter for Long-term Liver Expression.

 

The Promoter in the pLIVE® Vector Outperforms the CMV Promoter for Long-term Liver Expression. The pLIVE®-SEAP Vector (20 µg) and pCMV-SEAP (10 µg, CMV promoter-driven SEAP vector) were each delivered to four ICR mice using the hydrodynamic tail vein injection procedure and the TransIT®-QR Hydrodynamic Delivery Solution (MIR 5240). At the indicated days post-injection, serum from each mouse was collected and the level of SEAP activity present was determined using the Phospha-Light™ SEAP Assay Kit (Applied Biosystems). The average SEAP activity from each group is presented.

 

 

SKU: MIR 5420

 

Resources

Specifications

Storage Conditions
All Configurations: Store vector DNA at -20°C. Prior to use, thaw vector DNA at room temperature, vortex, and quick spin in a microcentrifuge.

Product Guarantee
All Configurations: 1 year

Usage Statement
All Configurations: For Research Use Only.

Animal Origin Statement
All Configurations: This product is animal origin free.

 

Technical Product Literature

Full Protocols
pLIVE® Vectors Full Protocol (PDF)

SDS
pLIVE® Vectors SDS (PDF)

Using transfection reagents and enhancers from Mirus has given our platform a competitive advantage. Increasing efficiency and lowering costs for all of our programs.

Sally Mader, PhD
ZYZ Theraputics