Applications | GMP Transfection for AAV Production

TransIT-VirusGEN® GMP Transfection Reagents and Kits

Nucleic Acid Delivery

Achieve higher titers and percent full AAV capsids
>50% savings on a cost per dose basis vs. the leading competitor
Universally platformable across all AAV serotypes

ISO 13485:2016 Certified

Completion of this comprehensive certification process underscores the quality of the processes used to support the company’s GMP product portfolio

View the certificate

The Highest Quality Grade for Cell & Gene Therapy

VirusGEN® is a proven transfection reagent combining industry-leading yield performance with real world economic
advantages by delivering a reduced cost per dose — all supported by comprehensive expertise for cell and gene therapy.

VirusGEN® specifications support virus production fit-for-purpose requirements.

Browse GMP products

Designed to be Biomimetic for Optimized Performance

What makes VirusGEN® unique?

Mirus proprietary lipid and polymer technology
Forms lipopolyplex with DNA (or nucleic acid)
Biomimetic behavior increases transfection efficiency

What benefit does this bring?

Higher titers vs. PEI (2-10x) and higher percent full AAV capsids

VirusGEN Outperforms Competitor Reagents in Various AAV Serotypes

VirusGEN Percent Full Titer Consistently Outperforms Competitors

Higher Titers Deliver Significant Cost Per Dose Savings

Documentation

Specifications

Storage Conditions:

VirusGEN® GMP AAV Transfection Kit: Multiple storage conditions – see individual bottles for specific recommendations
TransIT-VirusGEN® GMP Transfection Reagent: Store at -10 to -30°C

Product Guarantee:

All Configurations: Refer to Certificate of Analysis for Retest Date

Usage Statement:

All Configurations: For Research Use and Further Manufacturing; Not for Administration into Humans.

Animal Origin Statement:

All Configurations: This product is animal origin free.

Technical Product Literature

Full Protocols

TransIT-VirusGEN® GMP Protocol (PDF)
VirusGEN® GMP AAV Transfection Kit Protocol (PDF)

SDS

TransIT-VirusGEN® GMP SDS (PDF)
VirusGEN® GMP AAV Transfection Kit SDS (PDF)

Directly From Our Customers

Listen to the first-hand account of how Mirus helped researchers from St. Jude overcome the challenges with viral vector optimization to produce ground-breaking gene therapy for hemophilia. Go to the podcast >>

"Mirus sent me samples of TransIT-VirusGEN® to test with 293T cells to generate lentivirus. It outperforms the transfection reagent I was using before. The protocol is really simple, and the transfections are robust. I’m getting great virus production."

Dr. Steve Williams

Xyphos Inc.