Identification of a core gene-regulatory trajectory to terminal T cell dysfunction in human tumors and discovery of potential target genes involved in this process AuthorsDania Riegel
Journal 2023 (2023)
n/a:n/a
Automated Good Manufacturing Practice-Compatible CRISPR-Cas9 Editing of Hematopoietic Stem and Progenitor Cells for Clinical Treatment of ?-Hemoglobinopathies AuthorsGuillermo Ure�a-Bail�n, Milena Block, Tommaso Grandi, et al.
Journal The CRISPR Journal (2023)
6:5
Codon-specific KRAS mutations predict survival benefit of trifluridine/tipiracil in metastatic colorectal cancer AuthorsJoris van de Haar, Xuhui Ma, Salo N Ooft, et al.
Journal Nature Medicine (2023)
n/a:1
Generation of a SARS-CoV-2 reverse genetics system and novel human lung cell lines that exhibit high virus-induced cytopathology AuthorsJuveriya Qamar Khan, Megha Rohamare, Karthic Rajamanickam, et al.
Journal bioRxiv (2023)
n/a:2003
S: D614G and S: H655Y are gateway mutations that act epistatically to promote SARS-CoV-2 variant fitness AuthorsLeonid Yurkovetskiy, Shawn Egri, Chaitanya Kurhade, et al.
Journal bioRxiv (2023) 2003
Efficient CRISPR-Cas9-based genome editing of b-globin gene on erythroid cells from homozygous b 0 39-thalassemia patients AuthorsLucia Carmela Cosenza, Jessica Gasparello, Nicola Romanini, et al.
Journal Molecular Therapy-Methods & Clinical Development (2023)
n/a:n/a
Effect of HPSE and HPSE2 SNPs on the Risk of Developing Primary Paraskeletal Multiple Myeloma AuthorsOlga Ostrovsky, Katia Beider, Hila Magen, et al.
Journal Cells (2023)
12:913
Area postrema neurons mediate interleukin-6 function in cancer-associated cachexia AuthorsQingtao Sun, Danielle van de Lisdonk, Miriam Ferrer, et al.
Journal bioRxiv (2023) 2001
Product UsageProduct: Ingenio® Electroporation SolutionCell Type: Hypothalamus cells
Nucleic Acid: Plasmid DNA and CRISPR Guide RNA
Application: CRISPR/Cas9-Genome Editing
Disease Progression of WHIM Syndrome in an International Cohort of 66 Pediatric and Adult Patients AuthorsChristoph B Geier, Maryssa Ellison, Rachel Cruz, et al.
Journal Journal of Allergy and Clinical Immunology (2022)
n/a:1
Wwox Binding to the Murine Brca1-BRCT Domain Regulates Timing of Brip1 and CtIP Phospho-Protein Interactions with This Domain at DNA Double-Strand Breaks, and Repair Pathway Choice AuthorsDongju Park, Mehdi Gharghabi, Colleen Reczek, et al.
Journal International Journal of Molecular Sciences (2022)
23:3729
Deciphering the Role and Signaling Pathways of PKCα in Luminal A Breast Cancer Cells AuthorsEmilio M Serrano-Lopez, Teresa Coronado-Parra, Consuelo Marin-Vicente, et al.
Journal International Journal of Molecular Sciences (2022)
23:14023
Host Cell Redox Alterations Promote Latent HIV-1 Reactivation through Atypical Transcription Factor Cooperativity AuthorsEmily Cruz-Lorenzo, Nora-Guadalupe P Ramirez, Jeon Lee, et al.
Journal Viruses (2022)
14:2288
Neutralization and durability of 2 or 3 doses of the BNT162b2 vaccine against Omicron SARS-CoV-2 AuthorsHongjie Xia, Jing Zou, Chaitanya Kurhade, et al.
Journal Cell Host and Microbe (2022)
30:485
BND-22, a first-in-class humanized ILT2-blocking antibody, promotes antitumor immunity and tumor regression AuthorsIlana Mandel, Dana Haves Ziv, Ilana Goldshtein, et al.
Journal Journal for ImmunoTherapy of Cancer (2022)
10:e004859
Probing Ligand-Induced Changes in Cell Surface Expression of E-Selectin Using CRISPR/Cas9-Mediated Protein Tagging with HiBiT in Primary Human Endothelial Cells AuthorsLydia Ogrodzinski, Simon Platt, Cameron Alexander, et al.
Journal SSRN Electronic Journal (2022)
n/a Altered expression of the IGF2-H19 locus and mitochondrial respiratory complexes in adrenocortical carcinoma AuthorsPatrick Scicluna, Stefano Caramuta, Hanna Kjellin, et al.
Journal International Journal of Oncology (2022)
61:1
Adenosine A2A receptors control synaptic remodeling in the adult brain AuthorsXinli Xu, Rui O Beleza, Francisco Q Goncalves, et al.
Journal Scientific Reports (2022)
12:1
Neutralization of SARS-CoV-2 Omicron sublineages by 4 doses of the original mRNA vaccine AuthorsXuping Xie, Jing Zou, Chaitanya Kurhade, et al.
Journal Cell Reports (2022)
41:111729
Valproic acid disables the Nrf2 anti-oxidant response in acute myeloid leukaemia cells enhancing reactive oxygen species-mediated killing AuthorsYao Jiang, Andrew D Southam, Sandro Trova, et al.
Journal British Journal of Cancer (2022)
126:275
Deferasirox induces cyclin D1 degradation and apoptosis in mantle cell lymphoma in a reactive oxygen species- and GSK3β-dependent mechanism AuthorsAladin Samara, Saar Shapira, Ido Lubin, et al.
Journal British Journal of Haematology (2021)
192:747
Staphylococcus Aureus Induces Stat5 Dependent Mir-155 Expression In Cutaneous T-Cell Lymphoma (Ctcl) AuthorsAndreas Willerslev-Olsen, Lise Mette Rahbek Gjerdrum, Lise M Lindahl, et al.
Journal Journal of Investigative Dermatology (2021)
n/a:n/a
Staphylococcus aureus Induces Signal Transducer and Activator of Transcription 5‒Dependent miR-155 Expression in Cutaneous T-Cell Lymphoma AuthorsAndreas Willerslev-Olsen, Lise Mette Rahbek Gjerdrum, Lise M Lindahl, et al.
Journal Journal of Investigative Dermatology (2021)
n/a:n/a
Common ALS/FTD risk variants in UNC13A exacerbate its cryptic splicing and loss upon TDP-43 mislocalization AuthorsAnna-Leigh Brown, Oscar G Wilkins, Matthew J Keuss, et al.
Journal bioRxiv (2021)
n/a:2021.04.02.438170
Binding to PI(4,5)P2 is indispensable for secretion of B-cell clonogenic HIV-1 matrix protein p17 variants AuthorsAntonella Bugatti, Francesca Caccuri, Federica Filippini, et al.
Journal Journal of Biological Chemistry (2021)
297:100934
Characterization of lipoprotein lipase storage vesicles in 3T3-L1 adipocytes AuthorsBenjamin S Roberts, Chelsea Q Yang, Saskia B Neher
Journal Journal of Cell Science (2021)
135:jcs258734
Surface GluA1 and glutamate transmission are increased in VPS35 D620N neurons and altered by LRRK2 kinase inhibition AuthorsChelsie A Kadgien, Anusha Kamesh, Jaskaran Khinda, et al.
Journal bioRxiv (2021)
n/a:n/a
Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition AuthorsChelsie Kadgien, Anusha Kamesh, Jaskaran Khinda, et al.
Journal Research Square (2021)
n/a:n/a
The balance of mitochondrial fission and fusion in cortical axons depends on the kinases SadA and SadB AuthorsDanila Di Meo, Priyadarshini Ravindran, Pratibha Dhumale, et al.
Journal bioRxiv (2021)
n/a:n/a
The Rescue and the Selection of the Thermally Stabled Type O Vaccine Candidate Strains of Foot-and-Mouth Disease Virus AuthorsDong Li, Ya Gao, Pinghua Li, et al.
Journal Research Square (2021)
n/a:n/a
A heterochromatin inducing protein differentially recognizes self versus foreign Genomes AuthorsEric M Burtond, Ibukun A Akinyemi, Tiffany R Freyid, et al.
Journal PLoS Pathogens (2021)
17:e1009447
Structures of flavivirus RNA promoters suggest two binding modes with NS5 polymerase AuthorsEunhye Lee, Paul J Bujalowski, Tadahisa Teramoto, et al.
Journal Nature Communications (2021)
12:1
Nucleofection of adipose mesenchymal stem/stromal cells: Improved transfection efficiency for gmp grade applications AuthorsFrancesco Agostini, Carla Vicinanza, Gianni Biolo, et al.
Journal Cells (2021)
10:3412
Optogenetic control of receptors reveals distinct roles for actin- and Cdc42-dependent negative signals in chemotactic signal processing AuthorsGeorge RR Bell, Esther Rincón, Emel Akdoğan, et al.
Journal bioRxiv (2021)
n/a:n/a
Single-molecule imaging of microRNA-mediated gene silencing in cells AuthorsHotaka Kobayashi, Robert H Singer
Journal bioRxiv (2021)
n/a:2021.04.30.442050
Genetically modified attenuated salmonid alphavirus: A potential strategy for immunization of Atlantic salmon AuthorsIda Aksnes, Stine Braaen, Turhan Markussen, et al.
Journal Journal of Fish Diseases (2021)
n/a:n/a
Ecology and transmission of a dengue virus serotype 4 identified in wild Aedes aegypti in Florida AuthorsJasmine B Ayers, Xuping Xie, Heather Coatsworth, et al.
Journal bioRxiv (2021)
n/a:n/a
Role of mutational reversions and fitness restoration in Zika virus spread to the Americas AuthorsJianying Liu, Yang Liu, Chao Shan, et al.
Journal Nature Communications (2021)
12:1
Merkel cell polyomavirus T-antigens regulate DICER1 mRNA stability and translation through HSC70 AuthorsJiwei Gao, Hao Shi, Christofer Juhlin, et al.
Journal iScience (2021)
24:103264
Desmosomes polarize and integrate chemical and mechanical signaling to govern epidermal tissue form and function AuthorsJoshua A Broussard, Jennifer L Koetsier, Marihan Hegazy, et al.
Journal Current Biology (2021)
31:3275
A novel role of MNT as a negative regulator of REL and the NF-κB pathway AuthorsJudit Liaño-Pons, M Carmen Lafita-Navarro, Lorena García-Gaipo, et al.
Journal Oncogenesis (2021)
10:n/a
Bone Morphogenetic Protein Antagonist Gremlin-1 Increases Myofibroblast Transition in Dermal Fibroblasts: Implications for Systemic Sclerosis AuthorsLaura Duffy, John Henderson, Max Brown, et al.
Journal Frontiers in Cell and Developmental Biology (2021)
9:1451
MicroRNA-214 enriched exosomes from human cerebral endothelial cells (hCEC) sensitize hepatocellular carcinoma to anti-cancer drugs AuthorsLouie Semaan, Qingning Zeng, Yong Lu, et al.
Journal Oncotarget (2021)
12:185
IKAROS is required for the measured response of NOTCH target genes upon external NOTCH signaling AuthorsMaud Lemarie, Stefania Bottardi, Lionel Mavoungou, et al.
Journal PLoS Genetics (2021)
17:e1009478
Use of cell doublets for studying cytokinesis regulation reveals a new form of cytokinesis regression AuthorsNofar Levi-Dadon, Einat Panet, Shira Huri Ohev Shalom, et al.
Journal Research Square (2021)
n/a:n/a
ADAP1 promotes latent HIV-1 reactivation by selectively tuning a T cell signaling-transcriptional axis AuthorsNora-Guadalupe P Ramirez, Jeon Lee, Yue Zheng, et al.
Journal bioRxiv (2021)
n/a:n/a
Proximity-Dependent Biotinylation (BioID) of Integrin Interaction Partners AuthorsSatu Marja Myllymäki, Xiaonan Liu, Markku Varjosalo, et al.
Journal Methods in Molecular Biology (2021)
2217:57
A trans-complementation system for SARS-CoV-2 recapitulates authentic viral replication without virulence AuthorsXianwen Zhang, Yang Liu, Jianying Liu, et al.
Journal Cell (2021)
184:2229
Mammalian UPF3A and UPF3B activate NMD independently of their EJC binding 1 2 AuthorsZhongxia Yi, Rene M Arvola, Sean Myers, et al.
Journal bioRxiv (2021)
n/a:2021.07.02.450872
Kinetics of receptor tyrosine kinase activation define ERK signaling dynamics AuthorsAnatoly Kiyatkin, Iris K van Alderwerelt van Rosenburgh, Daryl E Klein, et al.
Journal Science Signaling (2020)
13:n/a
Staphylococcus aureus enterotoxins induce FOXP3 in neoplastic T cells in Sézary syndrome AuthorsAndreas Willerslev-Olsen, Terkild B Buus, Claudia Nastasi, et al.
Journal Blood Cancer Journal (2020)
10:1
The Mi-2 nucleosome remodeler and the Rpd3 histone deacetylase are involved in piRNA-guided heterochromatin formation AuthorsBruno Mugat, Simon Nicot, Carolina Varela-Chavez, et al.
Journal Nature Communications (2020)
11:1
Cross-platform validation of neurotransmitter release impairments in schizophrenia patient-derived NRXN1-mutant neurons AuthorsChang Hui Pak, Tamas Danko, Vincent R Mirabella, et al.
Journal bioRxiv (2020)
n/a:n/a
Targeted Protein Degradation Phenotypic Studies Using HaloTag CRISPR/Cas9 Endogenous Tagging Coupled with HaloPROTAC3 AuthorsElizabeth A Caine, Sarah D Mahan, Rebecca L Johnson, et al.
Journal Current Protocols in Pharmacology (2020)
91:e81
The Role of Desmoglein 1 in Gap Junction Turnover Revealed through the Study of SAM Syndrome AuthorsEran Cohen-Barak, Lisa M Godsel, Jennifer L Koetsier, et al.
Journal Journal of Investigative Dermatology (2020)
140:556
A promiscuous inflammasome sparks replication of a common tumor virus AuthorsEric M Burton, Raphaela Goldbach-Mansky, Sumita Bhaduri-McIntosh
Journal Proceedings of the National Academy of Sciences of the United States of America (2020)
117:1722
Systematically optimized BCMA/CS1 bispecific CAR-T cells robustly control heterogeneous multiple myeloma AuthorsEugenia Zah, Eunwoo Nam, Vinya Bhuvan, et al.
Journal bioRxiv (2020)
n/a:n/a
Evasion of Type I Interferon by SARS-CoV-2 AuthorsHongjie Xia, Zengguo Cao, Xuping Xie, et al.
Journal Cell Reports (2020)
33:108234
Mutation of N-glycosylation sites in Salmonid alphavirus (SAV) envelope proteins attenuate the virus in cell culture AuthorsIda Aksnes, Turhan Markussen, Stine Braaen, et al.
Journal Viruses (2020)
12:1071
CDK8 fine-tunes IL-6 transcriptional activities by limiting STAT3 resident time at the gene loci AuthorsJ Martinez-Fabregas, L Wang, E Pohler, et al.
Journal bioRxiv (2020)
33:108545
Interleukin-1 Receptor Associated Kinase (IRAK) signaling in Kaposi Sarcoma-associated herpesvirus (KSHV) induced Primary Effusion Lymphoma AuthorsJedediah Seltzer, Razia Moorad, Jason Schifano, et al.
Journal Journal of Virology (2020)
n/a:n/a
A novel role of MNT as a negative regulator of REL and the NF-κB pathway AuthorsJudit Liaño-Pons, M Carmen Lafita-Navarro, Carlota Colomer, et al.
Journal bioRxiv (2020)
n/a:n/a
L-Thyroxin and the Nonclassical Thyroid Hormone TETRAC Are Potent Activators of PPARÎ AuthorsLeonie Gellrich, Pascal Heitel, Jan Heering, et al.
Journal Journal of Medicinal Chemistry (2020)
63:6727
A role for α-Synuclein in axon growth and its implications in corticostriatal glutamatergic plasticity in Parkinson’s disease AuthorsMeir Schechter, Jessica Grigoletto, Suaad Abd-Elhadi, et al.
Journal Molecular Neurodegeneration (2020)
15:1
Docosahexaenoic fatty acid-containing phospholipids affect plasma membrane susceptibility to disruption by bacterial toxin-induced macroapertures AuthorsMeng Chen Tsai, Lucile Fleuriot, Sébastien Janel, et al.
Journal bioRxiv (2020)
n/a:n/a
Inhibiting endoplasmic reticulum stress decreases tumor burden in a mouse model for hepatocellular carcinoma AuthorsNatasa Pavlovic, Carlemi Calitz, Kessarin Thanapirom, et al.
Journal bioRxiv (2020)
n/a:826453
Inhibiting IRE1α-endonuclease activity decreases tumor burden in a mouse model for hepatocellular carcinoma AuthorsNataša Pavlović, Carlemi Calitz, Kessarin Thanapirom, et al.
Journal eLife (2020)
9:1
Mechanism of HPSE Gene SNPs Function: From Normal Processes to Inflammation, Cancerogenesis and Tumor Progression AuthorsOlga Ostrovsky, Israel Vlodavsky, Arnon Nagler
Journal Advances in Experimental Medicine and Biology (2020)
n/a:231
Comparison of tyrosine kinase domain properties for the neurotrophin receptors TrkA and TrkB AuthorsStephen C Artim, Anatoly Kiyatkin, Mark A Lemmon
Journal Biochemical Journal (2020)
n/a:n/a
O-GlcNAc modification of nuclear pore complexes accelerates bi-directional transport AuthorsTae Yeon Yoo, Timothy J Mitchison
Journal bioRxiv (2020)
n/a:n/a
EHD2 is a Predictive Biomarker of Chemotherapy Efficacy in Triple Negative Breast Carcinoma AuthorsWei Wei Shen, Ivan Bièche, Laetitia Fuhrmann, et al.
Journal Scientific Reports (2020)
10:n/a
Lamin C regulates genome organization after mitosis AuthorsXianrong Wong, Victoria E Hoskins, Jennifer C Harr, et al.
Journal bioRxiv (2020)
n/a:2020.07.28.213884
A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19 AuthorsXuping Xie, Antonio E Muruato, Xianwen Zhang, et al.
Journal Nature Communications (2020)
11:1
An Infectious cDNA Clone of SARS-CoV-2 AuthorsXuping Xie, Antonio Muruato, Kumari G Lokugamage, et al.
Journal Cell Host and Microbe (2020)
n/a:n/a
The EGFR Exon 19 Mutant L747-A750>P Exhibits Distinct Sensitivity to Tyrosine Kinase Inhibitors in Lung Adenocarcinoma AuthorsAnna Truini, Jacqueline Starrett, Tyler Stewart, et al.
Journal Clinical Cancer Research (2019)
n/a:clincanres.0780.2019
Identification of a miR-146b-FasL axis in the development of neutropenia in T large granular lymphocyte leukemia AuthorsBarbara Mariotti, Giulia Calabretto, Marzia Rossato, et al.
Journal Haematologica (2019)
n/a:haematol.2019.225060
SIRT7 mediates L1 elements transcriptional repression and their association with the nuclear lamina AuthorsBerta Vazquez, Joshua Thackray, Nicolas Simonet, et al.
Journal Nucleic Acids Research (2019)
n/a:n/a
A Strategy to Optimize the Generation of Stable Chromobody Cell Lines for Visualization and Quantification of Endogenous Proteins in Living Cells AuthorsBettina-Maria Keller, Julia Maier, Melissa Weldle, et al.
Journal Antibodies (2019)
8:10
Regulation of dendrite morphology and excitatory synapse formation by zDHHC15 AuthorsBhavin Shah, Jordan Shimell, Shernaz Bamji
Journal Journal of Cell Science (2019)
132:jcs. 230052
Product UsageProduct: Ingenio® Electroporation SolutionCell Type: Hippocampal neurons (rat, primary)
Nucleic Acid: shRNA-encoding plasmid DNA
Application: Gene Knockdown
ER reorganization and intracellular retention of CD58 are functionally independent properties of the human cytomegalovirus ER resident glycoprotein UL148 AuthorsChristopher Nguyen, Anthony Domma, Hongbo Zhang, et al.
Journal bioRxiv (2019)
n/a:746438
NDRG1 facilitates the replication and persistence of Kaposi's sarcoma-associated herpesvirus by interacting with the DNA polymerase clamp PCNA AuthorsFang Zhang, Deguang Liang, Xiaoxi Lin, et al.
Journal PLoS Pathogens (2019)
15 Phosphatidylinositol-3-phosphate-mediated actin domain formation linked to DNA synthesis upon insulin treatment in rat hepatoma-derived H4IIEC3 cells AuthorsFumi Kano, Masayuki Murata
Journal Biochimica et Biophysica Acta (BBA)-Molecular Cell Research (2019)
The rs17084733 variant in the KIT 3' UTR disrupts a miR-221/222 binding site in gastrointestinal stromal tumour: a sponge-like mechanism conferring disease susceptibility AuthorsGloria Ravegnini, Cesar Serrano, Vittorio Simeon, et al.
Journal Epigenetics (2019)
Ahi1 promotes Arl13b ciliary recruitment, regulates Arl13b stability and is required for normal cell migration AuthorsJesus Munoz-Estrada, Russell J Ferland
Journal Journal of Cell Science (2019)
132:jcs230680
Mitochondria supply ATP to the ER through a mechanism antagonized by cytosolic Ca2+ AuthorsJing Yong, Helmut Bischof, Sandra Burgstaller, et al.
Journal eLife (2019)
8:n/a
The Extracellular Domain of the B2 Integrin B Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity AuthorsLaura Ristow, Vy Tran, Kevin Schwartz, et al.
Journal mBio (2019)
10:e01459
Arp2/3 complex-driven spatial patterning of the B cell receptor (BCR) enhances immune synapse formation, BCR signaling, and cell activation AuthorsMadison Bolger-Munro, Kate Choi, Joshua Scurll, et al.
Journal bioRxiv (2019) 490698
Efficient Inhibition of Avian and Seasonal Influenza A Viruses by a Virus-Specific Dicer-Substrate Small Interfering RNA Swarm in Human Monocyte-Derived Macrophages and Dendritic Cells AuthorsMiao Jiang, Pamela Osterlund, Veera Westenius, et al.
Journal Journal of Virology (2019)
93:e01916
Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV AuthorsQingli Niu, Zhiqing Liu, Edrous Alamer, et al.
Journal Journal of Clinical Investigation (2019)
129:3361
wMelpop strain of Wolbachia infection of Aedes albopictus mosquito C6/36 cells modulates dengue virus-induced host cellular transcripts and induces critical sequence alterations in dengue viral genome. AuthorsTadahisa Teramoto, Xin Huang, Peter Armbruster, et al.
Journal Journal of Virology (2019)
Epstein-Barr virus microRNAs regulate B cell receptor signal transduction and lytic reactivation AuthorsYan Chen, Devin Fachko, Nikita S Ivanov, et al.
Journal PLoS Pathogens (2019)
15:e1007535
Tuning of delta-protocadherin adhesion through combinatorial diversity AuthorsAdam J Bisogni, Shila Ghazanfar, Eric O Williams, et al.
Journal eLife (2018)
7:e41050
ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells AuthorsAndrey Fadeev, Patricia Mendoza-Garcia, Uwe Irion, et al.
Journal Proceedings of the National Academy of Sciences (2018)
115:E630
Photoacoustic pigment relocalization sensor AuthorsAntonella Lauri, Dominik Soliman, Murad Omar, et al.
Journal bioRxiv (2018) 455022
SNAI2 upregulation is associated with an aggressive phenotype in fulvestrant-resistant breast cancer cells and is an indicator of poor response to endocrine therapy in estrogen receptor-positive metastatic breast cancer AuthorsCarla L Alves, Daniel Elias, Maria B Lyng, et al.
Journal Breast Cancer Research (2018)
20:60
Coupling integrin dynamics to cellular adhesion behaviors AuthorsCatherine G Galbraith, Michael W Davidson, James A Galbraith
Journal Biology Open (2018)
7:bio036806
Arkadia (RING Finger Protein 111) Mediates Sumoylation-Dependent Stabilization of Nrf2 Through K48-Linked Ubiquitination AuthorsDeneshia J Mcintosh, Treniqka S Walters, Ifeanyi J Arinze, et al.
Journal Cellular Physiology and Biochemistry (2018)
46:418
DNA vaccine expressing the non-structural proteins of Piscine orthoreovirus delay the kinetics of PRV infection and induces moderate protection against heart-and skeletal muscle inflammation in Atlantic salmon (Salmo salar) AuthorsHanne M Haatveit, Kjartan Hodneland, Stine Braaen, et al.
Journal Vaccine (2018)
36:7599
Filaggrin 2 deficiency results in abnormal cell-cell adhesion in the cornified cell layers and causes peeling skin syndrome type A AuthorsJanan Mohamad, Ofer Sarig, Lisa M Godsel, et al.
Journal Journal of Investigative Dermatology (2018)
138:1736
Activated heterotrimeric G protein alpha-i subunits inhibit Rap-dependent cell adhesion and promote cell migration AuthorsJesi Y To, Alan V Smrcka
Journal Journal of Biological Chemistry (2018)
293:1570
Clinical response of the novel activating ALK-I1171T mutation in neuroblastoma to the ALK inhibitor ceritinib AuthorsJikui Guan, Susanne Fransson, Joachim Tetteh T Siaw, et al.
Journal Molecular Case Studies (2018) mcs. a002550
Jumonji inhibitors overcome radioresistance in cancer through changes in H3K4 methylation at double-strand breaks AuthorsJuan Bayo, Tram Anh Tran, Lei Wang, et al.
Journal Cell Reports (2018)
25:1040
The mitochondrial inner membrane protein MPV17 prevents uracil accumulation in mitochondrial DNA AuthorsJudith R Alonzo, Chantel Venkataraman, Martha S Field, et al.
Journal Journal of Biological Chemistry (2018)
293:20285
Effects of single amino acid deficiency on mRNA translation are markedly different for methionine versus leucine AuthorsKevin M Mazor, Leiming Dong, Yuanhui Mao, et al.
Journal Scientific Reports (2018)
8 Increased Adhesion Of CML Cells By ABL1 Tyrosine Kinase Inhibitors Induce Tunneling Nanotubes AuthorsMaria Omsland, Vibeke Andresen, Maria Del Pilar Ayuda Duran, et al.
Journal bioRxiv (2018) 297838
Reliance upon ancestral mutations is maintained in colorectal cancers that heterogeneously evolve during targeted therapies AuthorsMariangela Russo, Simona Lamba, Annalisa Lorenzato, et al.
Journal Nature Communications (2018)
9:2287
Human platelet lysate as validated replacement for animal serum to assess chemosensitivity AuthorsMiriam Pons
Journal Altex (2018)
Loss of Wilms tumor 1 protein is a marker for apoptosis in response to replicative stress in leukemic cells AuthorsMiriam Pons, Claudia M Reichardt, Dorle Hennig, et al.
Journal Archives of Toxicology (2018) 1
Human platelet lysate as validated replacement for animal serum to assess chemosensitivity AuthorsMiriam Pons, Georg Nagel, Yanira Zeyn, et al.
Journal ALTEX-Alternatives to Animal Experimentation (2018)
SP140 regulates the expression of immune-related genes associated with multiple sclerosis and other autoimmune diseases by NF-KB inhibition AuthorsMohamad Karaky, Maria Fedetz, Victor Potenciano, et al.
Journal Human Molecular Genetics (2018)
27:4012
Identification of strong intron enhancer in the heparanase gene: effect of functional rs4693608 variant on HPSE enhancer activity in hematological and solid malignancies AuthorsOlga Ostrovsky, Ania Hava Grushchenko-Polaq, Katia Beider, et al.
Journal Oncogenesis (2018)
7:51
COMRADES determines in vivo RNA structures and interactions AuthorsOmer Ziv, Marta M Gabryelska, Aaron Tl Lun, et al.
Journal Nature Methods (2018)
15:785
Desmosomal cadherin association with Tctex-1 and cortactin-Arp2/3 drives perijunctional actin polymerization to promote keratinocyte delamination AuthorsOxana Nekrasova, Robert M Harmon, Joshua A Broussard, et al.
Journal Nature Communications (2018)
9:1053
Fragile X mental retardation protein is a Zika virus restriction factor that is antagonized by subgenomic flaviviral RNA AuthorsRuben Soto-Acosta, Xuping Xie, Chao Shan, et al.
Journal eLife (2018)
7:e39023
A glucose-responsive insulin therapy protects animals against hypoglycemia AuthorsRuojing Yang, Margaret Wu, Songnian Lin, et al.
Journal JCI Insight (2018)
3 Virus control of trafficking from sorting endosomes AuthorsSebastian Zeltzer, Carol A Zeltzer, Suzu Igarashi, et al.
Journal mBio (2018)
9:e00683
A Zeb2-miR-200c loop controls midbrain dopaminergic neuron neurogenesis and migration AuthorsShanzheng Yang, Enrique M Toledo, Pedro Rosmaninho, et al.
Journal Communications Biology (2018)
1:75
miR-181c-BRK1 axis plays a key role in actin cytoskeleton-dependent T cell function AuthorsShok Ping Lim, Nikolaos Ioannou, Alan G Ramsay, et al.
Journal Journal of Leukocyte Biology (2018)
103:855
Measuring NDC80 binding reveals the molecular basis of tension-dependent kinetochore-microtubule attachments AuthorsTae Yeon Yoo, Jeong-Mo Choi, William Conway, et al.
Journal bioRxiv (2018) 276212
KRAB-ZFP repressors enforce quiescence of oncogenic human herpesviruses AuthorsXiaofan Li, Eric M Burton, Siva Koganti, et al.
Journal Journal of Virology (2018) JVI. 00298
Regulation of gammaherpesvirus lytic replication by endoplasmic reticulum stress-induced transcription factors ATF4 and CHOP AuthorsXing-Chen Zhou, Si-Han Dong, Zhong-Shun Liu, et al.
Journal Journal of Biological Chemistry (2018) jbc. M117. 813675
The autophagy elongation complex (ATG5-12/16L1) positively regulates HCV replication and is required for wild-type membranous web formation AuthorsAhmed M Fahmy, Patrick Labonte
Journal Scientific Reports (2017)
7:40351
Pyk2 and FAK differentially regulate invadopodia formation and function in breast cancer cells AuthorsAlessandro Genna, Stefanie Lapetina, Nikola Lukic, et al.
Journal Journal of Cell Biology (2017) jcb. 201702184
FoxO4 negatively controls Tat-mediated HIV-1 transcription through the post-transcriptional suppression of Tat encoding mRNA AuthorsAlexandra Oteiza, Nadir Mechti
Journal Journal of General Virology (2017)
98:1864
NAMPT overexpression induces cancer stemness and defines a novel tumor signature for glioma prognosis AuthorsAntonio Lucena-Cacace, Daniel Otero-Albiol, Manuel P Jimenez-Garcia, et al.
Journal Oncotarget (2017)
8:99514
Regulation of Kif15 localization and motility by the C-terminus of TPX2 and microtubule dynamics AuthorsBarbara J. Mann, Sai K. Balchand, Patricia Wadsworth
Journal Molecular Biology of the Cell (2017)
28:65
A c-Myb mutant causes deregulated differentiation due to impaired histone binding and abrogated pioneer factor function AuthorsBettina M Fuglerud, Roza B Lemma, Pimthanya Wanichawan, et al.
Journal Nucleic Acids Research (2017)
45:7681
An Epstein-Barr virus microRNA blocks IL-1 signaling by targeting the interleukin-1 receptor 1 AuthorsCamille M Skinner, Nikita S Ivanov, Sarah A Barr, et al.
Journal Journal of Virology (2017) JVI. 00530
Editor's highlight: Thy1 (CD90) expression is reduced by the environmental chemical tetrabromobisphenol-A to promote adipogenesis through induction of microRNA-103 AuthorsCollynn F Woeller, E'lissa Flores, Stephen J Pollock, et al.
Journal Toxicological Sciences (2017)
157:305
EGFR ligands differentially stabilize receptor dimers to specify signaling kinetics AuthorsDaniel M Freed, Nicholas J Bessman, Anatoly Kiyatkin, et al.
Journal Cell (2017)
171:683
Human basonuclin 2 up-regulates a cascade set of interferon-stimulated genes with anti-cancerous properties in a lung cancer model AuthorsEgon Urgard, Anu Reigo, Eva Reinmaa, et al.
Journal Cancer Cell International (2017)
17:18
Engineering Structurally Interacting RNA (sxRNA) AuthorsFrancis Doyle, Sameer Lapsia, Salvatore Spadaro, et al.
Journal Scientific Reports (2017)
7:45393
Viral protein kinetics of piscine orthoreovirus infection in atlantic salmon blood cells AuthorsHanne Merethe Haatveit, Oystein Wessel, Turhan Markussen, et al.
Journal Viruses (2017)
9:49
Synthekines are surrogate cytokine and growth factor agonists that compel signaling through non-natural receptor dimers AuthorsIgnacio Moraga, Jamie B Spangler, Juan L Mendoza, et al.
Journal eLife (2017)
6:e22882
Pyruvate dehydrogenase has a major role in mast cell function, and its activity is regulated by mitochondrial microphthalmia transcription factor AuthorsIsraa Sharkia, Tal Hadad Erlich, Nadine Landolina, et al.
Journal Journal of Allergy and Clinical Immunology (2017)
140:204
Reversible methylation of m 6 A m in the 5' cap controls mRNA stability AuthorsJan Mauer, Xiaobing Luo, Alexandre Blanjoie, et al.
Journal Nature (2017)
541:371
Activated heterotrimeric G protein alpha-i subunits inhibit Rap-dependent cell adhesion and promote cell migration AuthorsJesi Y To, Alan V Smrcka
Journal Journal of Biological Chemistry (2017) jbc. RA117. 000964
MiR-126 affects brain-heart interaction after cerebral ischemic stroke AuthorsJieli Chen, Chengcheng Cui, Xiaoping Yang, et al.
Journal Translational Stroke Research (2017)
8:374
Novel Mechanisms of ALK Activation Revealed by Analysis of the Y1278S Neuroblastoma Mutation AuthorsJikui Guan, Yasuo Yamazaki, Damini Chand, et al.
Journal Cancers (2017)
9:149
Engineered epidermal progenitor cells can correct diet-induced obesity and diabetes AuthorsJiping Yue, Xuewen Gou, Yuanyuan Li, et al.
Journal Cell Stem Cell (2017)
21:256
Product UsageProduct: Ingenio® Electroporation SolutionCell Type: Epidermal basal cells (mouse, primary)
Nucleic Acid: Cas9 RNP
Application: CRISPR/Cas9-Genome Editing
Product UsageProduct: Ingenio® Electroporation SolutionCell Type: Epidermal basal cells (human, primary)
Nucleic Acid: Cas9 RNP
Application: CRISPR/Cas9-Genome Editing
FGD5 sustains vascular endothelial growth factor A (VEGFA) signaling through inhibition of proteasome-mediated VEGF receptor 2 degradation AuthorsJohan Heldin, Paul O'callaghan, Rodrigo Hernandez Vera, et al.
Journal Cellular Signalling (2017)
40:125
The role of the PI (3, 5) P 2 kinase TbFab1 in endo/lysosomal trafficking in Trypanosoma brucei AuthorsJulia K Gilden, Khan Umaer, Emilia K Kruzel, et al.
Journal Molecular and Biochemical Parasitology (2017)
214:52
Molecular Function Analysis of Rabies Virus RNA Polymerase L Protein by Using an L Gene-Deficient Virus AuthorsKento Nakagawa, Yuki Kobayashi, Naoto Ito, et al.
Journal Journal of Virology (2017)
91:e00826
The Cellular DNA Helicase ChlR1 Regulates Chromatin and Nuclear Matrix Attachment of the Human Papillomavirus 16 E2 Protein and High-Copy-Number Viral Genome Establishment AuthorsLeanne Harris, Laura Mcfarlane-Majeed, Karen Campos-Leon, et al.
Journal Journal of Virology (2017)
91:e01853
Folic acid-decorated polyamidoamine dendrimer exhibits high tumor uptake and sustained highly localized retention in solid tumors: its utility for local siRNA delivery AuthorsLeyuan Xu, W Andrew Yeudall, Hu Yang
Journal Acta Biomaterialia (2017)
57:251
Optogenetic control of the Dab1 signaling pathway AuthorsLiang Wang, Jonathan A Cooper
Journal Scientific Reports (2017)
7:43760
Alternative splicing of STAT3 is affected by RNA editing AuthorsLior Goldberg, Mor Abutbul-Amitai, Gideon Paret, et al.
Journal DNA and Cell Biology (2017)
36:367
Axon Death Pathways Converge on Axundead to Promote Functional and Structural Axon Disassembly AuthorsLukas J Neukomm, Thomas C Burdett, Andrew M Seeds, et al.
Journal Neuron (2017)
95:78
Efficient generation of somatic cell nuclear transfer-competent porcine cells with mutated alleles at multiple target loci by using CRISPR/Cas9 combined with targeted toxin-based selection system AuthorsMasahiro Sato, Kazuchika Miyoshi, Shingo Nakamura, et al.
Journal International Journal of Molecular Sciences (2017)
18:2610
RNA binding protein Quaking stabilizes Sirt2 mRNA during oligodendroglial differentiation AuthorsMerlin P Thangaraj, Kendra L Furber, Jotham K Gan, et al.
Journal Journal of Biological Chemistry (2017) jbc. M117. 775544
RNA-binding Protein Quaking Stabilizes Sirt2 mRNA during Oligodendroglial Differentiation AuthorsMerlin P. Thangaraj, Kendra L. Furber, Jotham K. Gan, et al.
Journal Journal of Biological Chemistry (2017)
292:5166
In-house made nucleofection buffer for efficient and cost effective transfection of RAW 264.7 macrophages AuthorsNeeraja P Alamuru-Yellapragada, Bandish Kapadia, Kishore Vl Parsa
Journal Biochemical and Biophysical Research Communications (2017)
487:247
Epidermal Growth Factor Receptor neddylation is regulated by a desmosomal-COP9 (Constitutive Photomorphogenesis 9) signalosome complex AuthorsNicole Ann Najor, Gillian Nicole Fitz, Jennifer Leigh Koetsier, et al.
Journal eLife (2017)
6:e22599
Chimeric CRISPR guides enhance Cas9 target specificity AuthorsNoah Jakimo, Pranam Chatterjee, Joseph M Jacobson
Journal bioRxiv (2017) 147686
D-4F increases microRNA-124a and reduces neuroinflammation in diabetic stroke rats AuthorsRuizhuo Ning, Poornima Venkat, Michael Chopp, et al.
Journal Oncotarget (2017)
8:95481
Serotype-specific interactions among functional domains of Dengue virus 2 non-structural proteins (NS) 5 and NS3 are crucial for viral RNA replication AuthorsTadahisa Teramoto, Anuradha Balasubramanian, Kyung H Choi, et al.
Journal Journal of Biological Chemistry (2017) jbc. M117. 775643
Chloroquine triggers Epstein-Barr virus replication through phosphorylation of KAP1/TRIM28 in Burkitt lymphoma cells AuthorsXiaofan Li, Eric M Burton, Sumita Bhaduri-Mcintosh
Journal PLoS Pathogens (2017)
13:e1006249
Loss of FOXO1 cooperates with TMPRSS2-ERG overexpression to promote prostate tumorigenesis and cell invasion AuthorsYinhui Yang, Alexandra M Blee, Dejie Wang, et al.
Journal Cancer Research (2017) canres. 0686.2017
ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype AuthorsYulia Haim, Matthias Bluher, Daniel Konrad, et al.
Journal Molecular Metabolism (2017)
6:725
BET bromodomain-mediated interaction between ERG and BRD4 promotes prostate cancer cell invasion AuthorsAlexandra M Blee, Shujun Liu, Liguo Wang, et al.
Journal Oncotarget (2016)
7:38319
Staphylococcus aureus enterotoxin A (SEA) stimulates STAT3 activation and IL-17 expression in cutaneous T-cell lymphoma AuthorsAndreas Willerslev-Olsen, Thorbjorn Krejsgaard, Lise M Lindahl, et al.
Journal Blood (2016) blood
Staphylococcal enterotoxin A (SEA) stimulates STAT3 activation and IL-17 expression in cutaneous T-cell lymphoma AuthorsAndreas Willerslev-Olsen, Thorbjorn Krejsgaard, Lise M. Lindahl, et al.
Journal Blood (2016)
127:1287
Lenalidomide stabilizes the erythropoietin receptor by inhibiting the E3 ubiquitin ligase RNF41 AuthorsAshley A Basiorka, Kathy L Mcgraw, Leentje De Ceuninck, et al.
Journal Cancer Research (2016) canres. 1756.2015
Lenalidomide Stabilizes the Erythropoietin Receptor by Inhibiting the E3 Ubiquitin Ligase RNF41 AuthorsAshley A. Basiorka, Kathy L. Mcgraw, Leentje De Ceuninck, et al.
Journal Cancer Research (2016)
76:3531
Influence of cortical synaptic input on striatal neuronal dendritic arborization and sensitivity to excitotoxicity in corticostriatal coculture AuthorsCaodu Buren, Gaqi Tu, Matthew P. Parsons, et al.
Journal Journal of Neurophysiology (2016)
116:380
High CDK6 Protects Cells from Fulvestrant-Mediated Apoptosis and is a Predictor of Resistance to Fulvestrant in Estrogen Receptor-Positive Metastatic Breast Cancer AuthorsCarla L Alves, Daniel Elias, Maria Lyng, et al.
Journal Clinical Cancer Research (2016)
High CDK6 Protects Cells from Fulvestrant-Mediated Apoptosis and is a Predictor of Resistance to Fulvestrant in Estrogen Receptor-Positive Metastatic Breast Cancer AuthorsCarla L. Alves, Daniel Elias, Maria Lyng, et al.
Journal Clinical Cancer Research (2016)
22:5514
Human Cytomegalovirus Can Procure Deoxyribonucleotides for Viral DNA Replication in the Absence of Retinoblastoma Protein Phosphorylation AuthorsChad V. Kuny, Robert F. Kalejta
Journal Journal of Virology (2016)
90:8634
An infectious cDNA clone of Zika virus to study viral virulence, mosquito transmission, and antiviral inhibitors AuthorsChao Shan, Xuping Xie, Antonio E Muruato, et al.
Journal Cell Host and Microbe (2016)
19:891
miR-145 Regulates Diabetes-Bone Marrow Stromal Cell-Induced Neurorestorative Effects in Diabetes Stroke Rats AuthorsChengcheng Cui, Xinchun Ye, Michael Chopp, et al.
Journal Stem Cells Translational Medicine (2016)
5:1656
miR-145 regulates diabetes-bone marrow stromal cell-induced neurorestorative effects in diabetes stroke rats AuthorsChengcheng Cui, Xinchun Ye, Michael Chopp, et al.
Journal Stem Cells Translational Medicine (2016)
5:1656
Dynamic regulation of neutrophil polarity and migration by the heterotrimeric G protein subunits G{alpha}i-GTP and G{beta}{gamma} AuthorsChinmay R. Surve, Jesi Y. To, Sundeep Malik, et al.
Journal Science Signaling (2016)
9:ra22
Reduced O-GlcNAcase expression promotes mitotic errors and spindle defects AuthorsChris Lanza, Ee Phie Tan, Zhen Zhang, et al.
Journal Cell Cycle (2016)
15:1363
Infectious salmon anaemia virus (ISAV) RNA binding protein encoded by segment 8 ORF2 and its interaction with ISAV and intracellular proteins AuthorsChristel M Olsen, Turhan Markussen, Bernd Thiede, et al.
Journal Viruses (2016)
8:52
Hemopoietic cell kinase (Hck) and p21-activated kinase 2 (PAK2) are involved in the down-regulation of CD1a lipid antigen presentation by HIV-1 Nef in dendritic cells AuthorsEiji Shinya, Masumi Shimizu, Atsuko Owaki, et al.
Journal Journal of Virology (2016)
487:285
Endoplasmic reticulum stress enhances fibrosis through IRE1{alpha}-mediated degradation of miR-150 and XBP-1 splicing AuthorsFemke Heindryckx, Francois Binet, Markella Ponticos, et al.
Journal EMBO Molecular Medicine (2016) emmm.201505925
Endoplasmic reticulum stress enhances fibrosis through IRE1{alpha}-mediated degradation of miR-150 and XBP-1 splicing AuthorsFemke Heindryckx, Francois Binet, Markella Ponticos, et al.
Journal EMBO Molecular Medicine (2016)
8:729
Cellular aspartyl proteases promote the unconventional secretion of biologically active HIV-1 matrix protein p17 AuthorsFrancesca Caccuri, Maria Luisa Iaria, Federica Campilongo, et al.
Journal Scientific Reports (2016)
6:38027
ASK1/JNK-mediated TAp63 activation controls the cell survival signal of baicalein-treated EBV-transformed B cells AuthorsGa Bin Park, Yeong Seok Kim, Hyun-Kyung Lee, et al.
Journal Molecular and Cellular Biochemistry (2016)
412:247
The non-structural protein uNS of piscine orthoreovirus (PRV) forms viral factory-like structures AuthorsHanne Merethe Haatveit, Ingvild B Nyman, Turhan Markussen, et al.
Journal Veterinary Research (2016)
47:5
The protein phosphatase 4-PEA15 axis regulates the survival of breast cancer cells AuthorsHiba N Mohammed, Mark R Pickard, Mirna Mourtada-Maarabouni
Journal Cellular Signalling (2016)
28:1389
The Epstein-Barr virus immunoevasins BCRF1 and BPLF1 are expressed by a mechanism independent of the canonical late pre-initiation complex AuthorsJessica Mckenzie, Francesc Lopez-Giraldez, Henri-Jacques Delecluse, et al.
Journal PLoS Pathogens (2016)
12:e1006008
MiR-126 contributes to human umbilical cord blood cell-induced neurorestorative effects after stroke in type-2 diabetic mice AuthorsJieli Chen, Ruizhuo Ning, Alex Zacharek, et al.
Journal Stem Cells (2016)
34:102
Increased expression of the frontotemporal dementia risk factor TMEM106B causes C9orf72-dependent alterations in lysosomes AuthorsJohanna I. Busch, Travis L. Unger, Nimansha Jain, et al.
Journal Human Molecular Genetics (2016) ddw127
Endoplasmic reticulum stress induced by tunicamycin increases resistin messenger ribonucleic acid through the pancreatic endoplasmic reticulum eukaryotic initiation factor 2alphs kinase-activating transcription factor 4-CAAT/enhancer binding protein-alpha homologous protein pathway in THP-1 human monocytes AuthorsJunpei Hamada, Hiroshi Onuma, Fumihiro Ochi, et al.
Journal Journal of Diabetes Investigation (2016)
7:312
Talin2-mediated traction force drives matrix degradation and cell invasion AuthorsLei Qi, Naser Jafari, Xiang Li, et al.
Journal Journal of Cell Science (2016)
129:3661
Constitutive Expression of GATA4 Dramatically Increases the Cardiogenic Potential of D3 Mouse Embryonic Stem Cells AuthorsLillian L Laemmle, Justus B Cohen, Joseph C Glorioso
Journal Open Biotechnology Journal (2016)
10:248
STAT5 induces miR-21 expression in cutaneous T cell lymphoma AuthorsLise M Lindahl, Simon Fredholm, Claudine Joseph, et al.
Journal Oncotarget (2016)
7:45730
Density-dependent regulation of glioma cell proliferation and invasion mediated by miR-9 AuthorsMark Katakowski, Nicholas Charteris, Michael Chopp, et al.
Journal Cancer Microenvironment (2016)
9:149
The hormone response element mimic sequence of GAS5 lncRNA is sufficient to induce apoptosis in breast cancer cells AuthorsMark R Pickard, Gwyn T Williams
Journal Oncotarget (2016)
7:10104
Multiple domains in the C-terminus of NMDA receptor GluN2B subunit contribute to neuronal death following in vitro ischemia AuthorsMarta M Vieira, Jeannette Schmidt, Joana S Ferreira, et al.
Journal Neurobiology of Disease (2016)
89:223
Dynamics inside the cancer cell attractor reveal cell heterogeneity, limits of stability, and escape AuthorsQin Li, Anders Wennborg, Erik Aurell, et al.
Journal PNAS (2016)
113:2672
HIF-1{alpha} regulates the interaction of chronic lymphocytic leukemia cells with the tumor microenvironment AuthorsRoberta Valsecchi, Nadia Coltella, Daniela Belloni, et al.
Journal Blood (2016)
127:1987
HIF-1alpha regulates the interaction of chronic lymphocytic leukemia cells with the tumor microenvironment AuthorsRoberta Valsecchi, Nadia Coltella, Daniela Belloni, et al.
Journal Blood (2016) blood
LPP inhibits collective cell migration during lung cancer dissemination AuthorsS Kuriyama, M Yoshida, S Yano, et al.
Journal Oncogene (2016)
35:952
Involvement of TonEBP/NFAT5 in osmoadaptative response of human retinal pigmented epithelial cells to hyperosmolar stress AuthorsSarah Libert, Francois Willermain, Celia Weber, et al.
Journal Molecular Vision (2016)
22:100
The polycystin complex mediates Wnt/Ca 2+ signalling AuthorsSeokho Kim, Hongguang Nie, Vasyl Nesin, et al.
Journal Nature Cell Biology (2016)
18:752
Myoglobin and the regulation of mitochondrial respiratory chain complex IV AuthorsTatsuya Yamada, Hisashi Takakura, Thomas Jue, et al.
Journal Journal of Physiology (2016)
594:483
Integrative analysis of miRNA and gene expression reveals regulatory networks in tamoxifen-resistant breast cancer AuthorsTejal Joshi, Daniel Elias, Jan Stenvang, et al.
Journal Oncotarget (2016)
7:57239
Molecular basis for antigenic diversity of genus Betanodavirus AuthorsValentina Panzarin, Anna Toffan, Miriam Abbadi, et al.
Journal PLoS ONE (2016)
11:e0158814
Deregulated KLF4 Expression in Myeloid Leukemias Alters Cell Proliferation and Differentiation through MicroRNA and Gene Targets AuthorsValerie A. Morris, Carrie L. Cummings, Brendan Korb, et al.
Journal Molecular and Cellular Biology (2016)
36:559
Dengue virus nonstructural protein 5 (NS5) assembles into a dimer with a unique methyltransferase and polymerase interface AuthorsValerie J Klema, Mengyi Ye, Aditya Hindupur, et al.
Journal PLoS Pathogens (2016)
12:e1005451
A TET2 rs3733609 C/T genotype is associated with predisposition to the myeloproliferative neoplasms harboring JAK2V617F and confers a proliferative potential on erythroid lineages AuthorsXiao-Hui Shen, Nan-Nan Sun, Ya-Fei Yin, et al.
Journal Oncotarget (2016)
7:9550
Activation of RhoA, but not Rac1, mediates early stages of S1P-induced endothelial barrier enhancement AuthorsXun E Zhang, Shaquria P Adderley, Jerome W Breslin
Journal PLoS ONE (2016)
11:e0155490
The HIV-1 protein Vpr impairs phagosome maturation by controlling microtubule-dependent trafficking AuthorsAudrey Dumas, Gabrielle Le-Bury, Marie-Anai, et al.
Journal Journal of Cell Biology (2015)
211:359
Thy1 (CD90) controls adipogenesis by regulating activity of the Src family kinase, Fyn AuthorsCollynn F. Woeller, Charles W. O''loughlin, Stephen J. Pollock, et al.
Journal FASEB Journal (2015)
29:920
Cell-Specific Establishment of Poliovirus Resistance to an Inhibitor Targeting a Cellular Protein AuthorsEkaterina G. Viktorova, Jules Nchoutmboube, Lauren A. Ford-Siltz, et al.
Journal J. Virology. (2015)
89:4372
Directed targeting of chromatin to the nuclear lamina is mediated by chromatin state and A-type lamins AuthorsJennifer C. Harr, Teresa Romeo Luperchio, Xianrong Wong, et al.
Journal Journal of Cell Biology (2015)
208:33
Stimulation of the RIG-I/MAVS Pathway by Polyinosinic:Polycytidylic Acid Upregulates IFN-{beta} in Airway Epithelial Cells with Minimal Costimulation of IL-8 AuthorsNurlan Dauletbaev, Maria Cammisano, Kassey Herscovitch, et al.
Journal Journal of Immunology (2015)
195:2829
Effects of kinesin-5 inhibition on dendritic architecture and microtubule organization AuthorsOlga I. Kahn, Vandana Sharma, Christian Gonzalez-Billault, et al.
Journal Molecular Biology of the Cell (2015)
26:66
Caveolin-3 Overexpression Attenuates Cardiac Hypertrophy via Inhibition of T-type Ca2+ Current Modulated by Protein Kinase C{alpha} in Cardiomyocytes AuthorsYogananda S. Markandeya, Laura J. Phelan, Marites T. Woon, et al.
Journal J. Biol. Chem. (2015)
290:22085
Molecular basis for specific viral RNA recognition and 2'-O-ribose methylation by the dengue virus nonstructural protein 5 (NS5) AuthorsYongqian Zhao, Tingjin Sherryl Soh, Siew Pheng Lim, et al.
Journal PNAS (2015)
112:14834
Role of ASIC1 in the development of chronic hypoxia-induced pulmonary hypertension AuthorsCarlos H. Nitta, David A. Osmond, Lindsay M. Herbert, et al.
Journal American Journal of Physiology Heart and Circulatory Physiology (2014)
306:H41
Regulation of Autophagic Activation by Rta of Epstein-Barr Virus via the Extracellular Signal-Regulated Kinase Pathway AuthorsChien-Hui Hung, Lee-Wen Chen, Wen-Hung Wang, et al.
Journal J. Virology. (2014)
88:12133
Regulation of Autophagic Activation by Rta of Epstein-Barr Virus via the Extracellular Signal-Regulated Kinase Pathway AuthorsChien-Hui Hung, Lee-Wen Chen, Wen-Hung Wang, et al.
Journal J. Virology. (2014)
88:12133
Disease mutations in desmoplakin inhibit Cx43 membrane targeting mediated by desmoplakin-EB1 interactions AuthorsDipal M. Patel, Adi D. Dubash, Geri Kreitzer, et al.
Journal Journal of Cell Biology (2014)
206:779
Repression of the Proapoptotic Cellular BIK/NBK Gene by Epstein-Barr Virus Antagonizes Transforming Growth Factor {beta}1-Induced B-Cell Apoptosis AuthorsEva M. Campion, Roya Hakimjavadi, Sinead T. Loughran, et al.
Journal J. Virology. (2014)
88:5001
The Molecular Basis of Leukocyte Adhesion Involving Phosphatidic Acid and Phospholipase D AuthorsFrancis Speranza, Madhu Mahankali, Karen M. Henkels, et al.
Journal J. Biol. Chem. (2014)
289:28885
The NKG2D Ligand ULBP2 Is Specifically Regulated through an Invariant Chain-Dependent Endosomal Pathway AuthorsFranziska Uhlenbrock, Michael Hagemann-Jensen, Stephanie Kehlet, et al.
Journal Journal of Immunology (2014)
193:1654
N-Glycosylation of Asparagine 8 Regulates Surface Expression of Major Histocompatibility Complex Class I Chain-related Protein A (MICA) Alleles Dependent on Threonine 24 AuthorsMaiken Mellergaard, Sarah Line Skovbakke, Christine L. Schneider, et al.
Journal J. Biol. Chem. (2014)
289:20078
Bidirectional Control of Postsynaptic Density-95 (PSD-95) Clustering by Huntingtin AuthorsMatthew P. Parsons, Rujun Kang, Caodu Buren, et al.
Journal J. Biol. Chem. (2014)
289:3518
Product UsageProduct: Ingenio® Electroporation SolutionCell Type: Striatal neurons (mouse, primary)
Nucleic Acid: Plasmid DNA
Application: Primary Cell Electroporation
The Selenium Metabolite Methylselenol Regulates the Expression of Ligands That Trigger Immune Activation through the Lymphocyte Receptor NKG2D AuthorsMichael Hagemann-Jensen, Franziska Uhlenbrock, Stephanie Kehlet, et al.
Journal J. Biol. Chem. (2014)
289:31576
IRF5 is a target of BCR-ABL kinase activity and reduces CML cell proliferation AuthorsMichele Massimino, Maria Letizia Consoli, Maria Mesuraca, et al.
Journal Carcinogenesis (2014)
35:1132
Genotypic and Phenotypic Analyses of Hepatitis C Virus Variants Observed in Clinical Studies of VX-222, a Nonnucleoside NS5B Polymerase Inhibitor AuthorsMin Jiang, Eileen Z. Zhang, Andrzej Ardzinski, et al.
Journal Antimicrobial Agents and Chemotherapy (2014)
58:5456
Substitution of NS5 N-terminal Domain of Dengue Virus Type 2 RNA with Type 4 Domain Caused Impaired Replication and Emergence of Adaptive Mutants with Enhanced Fitness AuthorsTadahisa Teramoto, Siwaporn Boonyasuppayakorn, Misty Handley, et al.
Journal J. Biol. Chem. (2014)
289:22385
Cell culture and Drosophila model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma AuthorsDamini Chand, et al.
Journal Disease Models and Mechanisms (2013)
6:373
Sorafenib Inhibits Cell Migration and Stroma-Mediated Bortezomib Resistance by Interfering B-cell Receptor Signaling and Protein Translation in Mantle Cell Lymphoma AuthorsSilvia Xargay-Torrent, et al.
Journal Clinical Cancer Research (2013)
19:586
DNA-dependent Activator of Interferon-regulatory Factors (DAI) Promotes Lupus Nephritis by Activating the Calcium Pathway AuthorsWeijuan Zhang, et al.
Journal Journal of Biological Chemistry (2013)
288:13534
Myeloid Cell IL-10 Production in Response to Leishmania Involves Inactivation of Glycogen Synthase Kinase-3{beta} Downstream of Phosphatidylinositol-3 Kinase AuthorsDevki Nandan, et al.
Journal Journal of Immunology (2012)
188:367
Protein-protein-interaction Network Organization of the Hypusine Modification System AuthorsHenning Sievert, et al.
Journal Molecular and Cellular Proteomics (2012)
11:1289
The transcription factor Th-POK negatively regulates Th17 differentiation in V{alpha}14i NKT cells AuthorsIsaac Engel, et al.
Journal Blood (2012)
120:4524
On the Roles and Regulation of Chondroitin Sulfate and Heparan Sulfate in Zebrafish Pharyngeal Cartilage Morphogenesis AuthorsKatarina Holmborn, et al.
Journal Journal of Biological Chemistry (2012)
287:33905
Identifying and Targeting ROS1 Gene Fusions in Non-Small Cell Lung Cancer AuthorsKurtis D. Davies, et al
Journal Clinical Cancer Research (2012)
18:4570
Counteracting Autophagy Overcomes Resistance to Everolimus in Mantle Cell Lymphoma AuthorsLaia Rosich, et al.
Journal Clinical Cancer Research (2012)
18:5278
Regulation of Autophagy and Its Associated Cell Death by "Sphingolipid Rheostat": RECIPROCAL ROLE OF CERAMIDE AND SPHINGOSINE 1-PHOSPHATE IN THE MAMMALIAN TARGET OF RAPAMYCIN PATHWAY AuthorsMakoto Taniguchi, et al.
Journal Journal of Biological Chemistry (2012)
287:39898
Cot/tpl2-MKK1/2-Erk1/2 controls mTORC1-mediated mRNA translation in Toll-like receptor-activated macrophages AuthorsMarta Lopez-Pelaez, et al.
Journal Molecular Biology of the Cell (2012)
23:2982
L-Plastin Regulates Polarization and Migration in Chemokine-Stimulated Human T Lymphocytes AuthorsMichael Freeley, et al.
Journal Journal of Immunology (2012)
188:6357
Vav1 Oncogenic Mutation Inhibits T Cell Receptor-induced Calcium Mobilization through Inhibition of Phospholipase C{gamma}1 Activation AuthorsMira Knyazhitsky, et al.
Journal Journal of Biological Chemistry (2012)
287:19725
Viral mitochondria-localized inhibitor of apoptosis (UL37 exon 1 protein) does not protect human neural precursor cells from human cytomegalovirus-induced cell death AuthorsRichard L. Hildreth, et al.
Journal Journal of General Virology (2012)
93:2436
The human Pat1b protein: a novel mRNA deadenylation factor identified by a new immunoprecipitation technique AuthorsAntonio Totaro, et al.
Journal Nucleic Acids Research (2011)
39:635
Importin beta plays an essential role in the regulation of the LysRS-Ap(4)A pathway in immunologically activated mast cell AuthorsCarmi-Levy I, Motzik A, Ofir-Birin Y, Yagil Z, Yang CM, Kemeny DM, Han JM, Kim S, Kay G, Nechushtan H, Suzuki R, Rivera J, Razin E
Journal Molecular Biology of the Cell (2011)
31(10):2111 - 2121
Evidence for a conserved function of heart and neural crest derivatives expressed transcript 2 in mouse and human decidualization AuthorsD V Huyen, B M Bany
Journal Reproduction (2011)
142:353
Down-regulation of cytokine-induced interleukin-8 requires inhibition of p38 mitogen-activated protein kinase (MAPK) via MAPK phosphatase 1-dependent and -independent mechanism AuthorsDauletbaev N, Eklove D, Mawji N, Iskandar M, Di Marco S, Gallouzi IE, Lands LC
Journal Journal of Biological Chemistry (2011)
286(18):15998-16007
Targeting Cattle-Borne Zoonoses and Cattle Pathogens Using a Novel Trypanosomatid-Based Delivery System AuthorsG. Adam Mott
Journal PLoS Pathogens (2011)
7(10):e1002340
SKP2 Oncogene Is a Direct MYC Target Gene and MYC Down-regulates p27KIP1 through SKP2 in Human Leukemia Cells AuthorsGabriel Bretones, Juan C. Acosta, Juan M. Caraballo, Nuria Ferrandiz, M. Teresa Gomez-Casares, Marta Albajar, Rosa Blanco, Paula Ruiz, Wen-Chun Hung, M. Pilar Albero, Ignacio Perez-Roger, Javier Leon
Journal Journal of Biological Chemistry (2011)
286:9815-9825
The Hsp90 inhibitor IPI-504 overcomes bortezomib resistance in mantle cell lymphoma in vitro and in vivo by down-regulation of the prosurvival ER chaperone BiP/Grp78 AuthorsGael Roue, et al.
Journal Blood (2011)
117:1270
Identification of cis-acting elements in the 3'-untranslated region of the dengue virus type 2 RNA that modulate translation and replicatio AuthorsManzano M, Reichert ED, Polo S, Falgout B, Kasprzak W, Shapiro BA, Padmanabhan R
Journal Journal of Biological Chemistry (2011)
286(25):22521-22534
TCR-Induced Activation of LFA-1 Involves Signaling through Tiam1 AuthorsMikaela Gronholm, et al.
Journal Journal of Immunology (2011)
187:3613
The human T-cell leukemia virus type 1 oncoprotein tax controls forkhead box O4 activity through degradation by the proteasom AuthorsOteiza A, Mechti N
Journal Journal of Virology (2011)
85(13):6480-6491
Vorinostat-induced apoptosis in mantle cell lymphoma is mediated by acetylation of proapoptotic BH3-only gene promoter AuthorsXargay-Torrent S, López-Guerra M, Saborit-Villarroya I, Rosich L, Campo E, Roué G, Colomer D
Journal Clinical Cancer Research (2011)
17(12):3956-3968
Inhibition of Dengue Virus by Targeting Viral NS4B Protein AuthorsXuping Xie, et al.
Journal Journal of Virology (2011)
85:11183
Caveolin-3 Regulates Protein Kinase A Modulation of the CaV3.2 (α1H) T-type Ca2+ Channels AuthorsYogananda S. Markandeya, Jonathan M. Fahey, Florentina Pluteanu, Leanne L. Cribbs, and Ravi C. Balijepalli
Journal Journal of Biological Chemistry (2011)
286:2433-2444
OCRL1 function in renal epithelial membrane traffi AuthorsCui S, Guerriero CJ, Szalinski CM, Kinlough CL, Hughey RP, Weisz OA
Journal American Journal of Physiology (2010)
298:F335-F345
Flexibility between the Protease and Helicase Domains of the Dengue Virus NS3 Protein Conferred by the Linker Region and Its Functional Implications AuthorsDahai Luo, Na Wei, Danny N. Doan, Prasad N. Paradkar, Yuwen Chong, Andrew D. Davidson, Masayo Kotaka, Julien Lescar, and Subhash G. Vasudevan
Journal Journal of Biological Chemistry (2010)
285 :18817 - 18827
Nucleofection disrupts tight junction fence function to alter membrane polarity of renal epithelial cells AuthorsDi Mo, Beth A. Potter, Carol A. Bertrand, Jeffrey D. Hildebrand, Jennifer R. Bruns, and Ora A. Weisz.
Journal American Journal of Physiology (2010)
299:F1178-F1184
Porcine Reproductive and Respiratory Syndrome Virus Nonstructural Protein 1β Modulates Host Innate Immune Response by Antagonizing IRF3 Activation AuthorsLalit K. Beura, Saumendra N. Sarkar, Byungjoon Kwon, Sakthivel Subramaniam, Clinton Jones, Asit K. Pattnaik, and Fernando A. Osorio
Journal Journal of Virology (2010)
84:1574 - 1584
T Cell Activation Leads to Protein Kinase C{theta}-Dependent Inhibition of TGF-{beta} Signaling AuthorsMartin Giroux, Jean-Sebastien Delisle, Alan O'Brien, Marie-Josee Hebert, Claude Perreault
Journal Journal of Immunology (2010)
185:1568-1576
Appearance of the Novel Activating F1174S ALK Mutation in Neuroblastoma Correlates with Aggressive Tumor Progression and Unresponsiveness to Therapy AuthorsTommy Martinsson, Therese Eriksson, Jonas Abrahamsson, Helena Caren, Magnus Hansson, Per Kogner, Sattu Kamaraj
Journal Cancer Research (2010)
71(1):98-105
ZFP36L1 negatively regulates erythroid differentiation of CD34+ hematopoietic stem cells by interfering with the Stat5b pathwa AuthorsVignudelli T, Selmi T, Martello A, Parenti S, Grande A, Gemelli C, Zanocco-Marani T, Ferrari S
Journal Molecular Biology of the Cell (2010)
21(19):3340-3351