Isocotoin suppresses hepatitis E virus replication through inhibition of heat shock protein 90 AuthorsIla Nimgaonkar, Nicholas F Archer, Isabelle Becher, et al.
Journal Antiviral Research (2021)
185:104997
Defective viral genomes from chikungunya virus are broad-spectrum antivirals and prevent virus dissemination in mosquitoes AuthorsLaura I Levi, Veronica V. Rezelj, Annabelle Henrion-Lacritick, et al.
Journal PLoS Pathogens (2021)
17:e1009110
The CD147 Protein Complex Is Involved in Entry of Chikungunya Virus and Related Alphaviruses in Human Cells AuthorsLien De Caluwé, Sandra Coppens, Katleen Vereecken, et al.
Journal Frontiers in Microbiology (2021)
12:352
Ionizable lipid nanoparticles for in utero mRNA delivery AuthorsRachel S Riley, Meghana V. Kashyap, Margaret M Billingsley, et al.
Journal Science Advances Journal (2021)
7:eaba1028
N 6-methyladenosine modification of HIV-1 RNA suppresses type-I interferon induction in differentiated monocytic cells and primary macrophages AuthorsShuliang Chen, Sameer Kumar, Constanza E Espada, et al.
Journal PLoS Pathogens (2021)
17:e1009421
MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells AuthorsXin Yin, Laura Riva, Yuan Pu, et al.
Journal Cell Reports (2021)
34:108628
Zebrafish as an animal model for the antiviral RNA interference pathway AuthorsYanxin Ren, Xueyu Li, Zhonghui Tian, et al.
Journal Journal of General Virology (2021)
n/a:1552
SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses AuthorsAbhik K Banerjee, Mario R Blanco, Emily A Bruce, et al.
Journal Cell (2020)
n/a:n/a
Generation of Human Neutrophils from Induced Pluripotent Stem Cells in Chemically Defined Conditions Using ETV2 Modified mRNA AuthorsAditi Majumder, Kran Suknuntha, David Bennin, et al.
Journal STAR Protocols (2020)
1:100075
Product UsageProduct: TransIT®-mRNA Transfection KitCell Type: Induced pluripotent stem cells (iPSC)
Nucleic Acid: mRNA
Application: Gene/Protein Expression
Analysis of RNA–DNA triplex structures in vitro and in vivo AuthorsAnna Postepska-Igielska, Alena Blank-Giwojna, Ingrid Grummt
Journal Methods in Molecular Biology (2020)
2161:229
Mechanisms of Innate Immune Activation by a Hybrid Alphavirus-Rhabdovirus Vaccine Platform AuthorsAnthony M Marchese, Carolina Chiale, Safiehkhatoon Moshkani, et al.
Journal Journal of Interferon & Cytokine Research (2020)
40:92
Polylactide-Based Reactive Micelles as a Robust Platform for mRNA Delivery AuthorsCéline Lacroix, Almudena Humanes, Céline Coiffier, et al.
Journal Pharmaceutical Research (2020)
37:30
Hypervariable Domain of nsP3 of Eastern Equine Encephalitis Virus Is a Critical Determinant of Viral Virulence AuthorsChetan D Meshram, Nikita Shiliaev, Elena I Frolova, et al.
Journal Journal of Virology (2020)
94:n/a
Ribosome Collisions Trigger General Stress Responses to Regulate Cell Fate AuthorsColin Chih Chien Wu, Amy Peterson, Boris Zinshteyn, et al.
Journal Cell (2020)
182:404
A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice AuthorsDorottya Laczkó, Michael J Hogan, Sushila A Toulmin, et al.
Journal Immunity (2020)
53:724
Antifungal triazole posaconazole targets an early stage of the parechovirus A3 life cycle AuthorsEric Rhoden, Terry Fei Fan Ng, Ray Campagnoli, et al.
Journal Antimicrobial Agents and Chemotherapy (2020)
64:n/a
Distinct Inductions of and Responses to Type I and Type III Interferons Promote Infections in Two SARS-CoV-2 Isolates AuthorsFu Hsin, Tai-Ling Chao, Yun-Rui Chan, et al.
Journal bioRxiv (2020)
n/a:n/a
HBV-Induced Increased N6 Methyladenosine Modification of PTEN RNA Affects Innate Immunity and Contributes to HCC AuthorsGeon-Woo Kim, Hasan Imam, Mohsin Khan, et al.
Journal Hepatology (2020)
n/a:n/a
A Multiplexed Barcodelet Single-Cell RNA-Seq Approach Elucidates Combinatorial Signaling Pathways that Drive ESC Differentiation AuthorsGrace Hui Ting Yeo, Lin Lin, Celine Yueyue Qi, et al.
Journal Cell Stem Cell (2020)
26:938
The mRNA cap 2’O methyltransferase CMTR1 regulates the expression of certain interferon-stimulated genes AuthorsGraham D Williams, Nandan S Gokhale, Daltry L Snider, et al.
Journal American Society for Microbiology - mSphere (2020)
5:2020.03.05.980045
The mRNA Cap 2′- O -Methyltransferase CMTR1 Regulates the Expression of Certain Interferon-Stimulated Genes AuthorsGraham D Williams, Nandan S Gokhale, Daltry L Snider, et al.
Journal mSphere (2020)
5:n/a
Intracranial Delivery of Synthetic mRNA Using Common Transfection Reagent AuthorsHao Peng, Xingrong Guo, Jinjuan He, et al.
Journal Research Square (2020)
n/a A Sensitive Yellow Fever Virus Entry Reporter Identifies Valosin-Containing Protein (VCP/p97) as an Essential Host Factor for Flavivirus Uncoating AuthorsHarish N Ramanathan, Shuo Zhang, Florian Douam, et al.
Journal mBio (2020)
11:n/a
Sphingomyelin Is Essential for the Structure and Function of the Double-Membrane Vesicles in Hepatitis C Virus RNA Replication Factories AuthorsHossam Gewaid, Haruyo Aoyagi, Minetaro Arita, et al.
Journal Journal of Virology (2020)
94:n/a
Peli1 signaling blockade attenuates congenital zika syndrome AuthorsHuanle Luo, Guangyu Li, Binbin Wang, et al.
Journal PLoS Pathogens (2020)
16:e1008538
An infectious clone of enterovirus 71(EV71) that is capable of infecting neonatal immune competent mice without adaptive mutations AuthorsHuiying Zhang, Zhigang Song, Jingyi Zou, et al.
Journal Emerging Microbes and Infections (2020)
9:427
RTP4 Is a Potent IFN-Inducible Anti-flavivirus Effector Engaged in a Host-Virus Arms Race in Bats and Other Mammals AuthorsIan N Boys, Elaine Xu, Katrina B Mar, et al.
Journal Cell Host and Microbe (2020)
28:712
Splicing modulators elicit global translational repression by condensate-prone proteins translated from introns AuthorsJagat Krishna Chhipi Shrestha, Tilman Schneider-Poetsch, Takehiro Suzuki, et al.
Journal bioRxiv (2020)
n/a:n/a
Development of a new oral poliovirus vaccine for the eradication end game using codon deoptimization AuthorsJennifer L Konopka-Anstadt, Ray Campagnoli, Annelet Vincent, et al.
Journal npj Vaccines (2020)
5:1
An Alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates AuthorsJesse H Erasmus, Amit P Khandhar, Megan A O’Connor, et al.
Journal Science Translational Medicine (2020)
12:n/a
Tumor-responsive, multifunctional CAR-NK cells cooperate with impaired autophagy to infiltrate and target glioblastoma AuthorsJiao Wang, Sandra Toregrosa-Allen, Bennett D Elzey, et al.
Journal bioRxiv (2020)
n/a:n/a
An Amphipathic Alpha-Helix Domain from Poliovirus 2C Protein Tubulate Lipid Vesicles AuthorsJobin Varkey, Jiantao Zhang, Junghyun Kim, et al.
Journal Viruses (2020)
12:1466
Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase AuthorsJustin T Ernst, Peggy A Thompson, Christian Nilewski, et al.
Journal Journal of Medicinal Chemistry (2020)
63:5879
Dengue and Zika virus infection are impaired by small molecule ER proteostasis regulator 147 in an ATF6-independent manner AuthorsKatherine M Almasy, Jonathan P Davies, Samantha M Lisy, et al.
Journal bioRxiv (2020)
n/a:n/a
Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates AuthorsKevin O Saunders, Norbert Pardi, Robert Parks, et al.
Journal bioRxiv (2020)
n/a:n/a
Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection AuthorsMatthew Lee Goodwin, Helen S Webster, Hsuan-Yuan Wang, et al.
Journal bioRxiv (2020)
n/a:n/a
Structural basis for hijacking of the host ACBD3 protein by bovine and porcine enteroviruses and kobuviruses AuthorsMiroslav Smola, Vladimira Horova, Evzen Boura, et al.
Journal Archives of Virology (2020)
165:355
Synthesis of low immunogenicity RNA with high-temperature in vitro transcription AuthorsMonica Z Wu, Haruichi Asahara, George Tzertzinis, et al.
Journal RNA (2020)
26:345
Oncolytic Activity of Targeted Picornaviruses Formulated as Synthetic Infectious RNA AuthorsNoura B Elsedawy, Rebecca A Nace, Stephen J Russell, et al.
Journal Molecular Therapy - Oncolytics (2020)
17:484
Hepatitis e virus replication in human intestinal cells AuthorsOlivier Marion, Sebastien Lhomme, Manon Nayrac, et al.
Journal Gut (2020)
69:901
Wolbachia Inhibits Binding of Dengue and Zika Viruses to Mosquito Cells AuthorsPeng Lu, Qiang Sun, Ping Fu, et al.
Journal Frontiers in Microbiology (2020)
11:1750
A single-dose mRNA vaccine provides a long-term protection for hACE2 transgenic mice from SARS-CoV-2 AuthorsQingrui Huang, Kai Ji, Siyu Tian, et al.
Journal Research Square (2020)
n/a:n/a
Translation of small downstream ORFs enhances translation of canonical main open reading frames AuthorsQiushuang Wu, Matthew Wright, Madelaine M Gogol, et al.
Journal EMBO Journal (2020)
39:e104763
A slow, efficient and safe nanoplatform of tailored ZnS QD-mycophenolic acid conjugates for in vitro drug delivery against dengue virus 2 genome replication AuthorsRanjeet Dungdung, Manikanta Bayal, Lathika Valliyott, et al.
Journal Nanoscale Advances (2020)
n/a:n/a
Liver-expressed Cd302 and Cr1l limit hepatitis C virus cross-species transmission to mice AuthorsRichard JP Brown, Birthe Tegtmeyer, Julie Sheldon, et al.
Journal Science Advances Journal (2020)
6:eabd3233
Subgenomic RNA from Dengue Virus Type 2 Suppresses Replication of Dengue Virus Genomes and Interacts with Virus-Encoded NS3 and NS5 Proteins AuthorsSai Wang, Kitti WK Chan, Kishore B Naripogu, et al.
Journal ACS Infectious Diseases (2020)
6:436
Human IFITM3 restricts Chikungunya virus and Mayaro virus infection and is susceptible to virus-mediated counteraction 2 3 AuthorsSergej Franz, Thomas Zillinger, Fabian Pott, et al.
Journal bioRxiv (2020)
n/a:2020.09.11.292946
Generation and preliminary characterization of vertebrate-specific replication-defective Zika virus AuthorsShengfeng Wan, Shengbo Cao, Xugang Wang, et al.
Journal Virology (2020)
552:73
An Efficient and Footprint-Free Protocol for the Transdifferentiation of Hepatocytes Into Insulin-Producing Cells With IVT mRNAs AuthorsShinan Ma, Mengjie Yang, Wenhui Zhou, et al.
Journal Frontiers in Genetics (2020)
11:575
N6-methyladenosine modification of HIV-1 RNA evades RIG-I-mediated sensing to suppresses type-I interferon induction in monocytic cells AuthorsShuliang Chen, Sameer Kumar, Nagaraja Tirumuru, et al.
Journal bioRxiv (2020)
n/a:n/a
Adapting CRISPR/Cas9 System for Targeting Mitochondrial Genome AuthorsSyed-Rehan A Hussain, Mehmet E Yalvac, Bendict Khoo, et al.
Journal bioRxiv (2020)
n/a:2020.02.11.944819
Host-derived Circular RNAs Display Proviral Activities in Hepatitis C Virus - Infected Cells AuthorsTzu Chun Chen, Marc Tallo-Parra, Sebastian Kadener, et al.
Journal bioRxiv (2020)
16:e1008346
Persistent infection with a rabbit hepatitis E virus created by a reverse genetics system AuthorsWenjing Zhang, Yasushi Ami, Yuriko Suzaki, et al.
Journal Transboundary and Emerging Diseases (2020)
n/a:n/a
Identification of functional cis-acting RNA elements in the hepatitis E virus genome required for viral replication AuthorsXiaohui Ju, Guangtao Xiang, Mingli Gong, et al.
Journal PLoS Pathogens (2020)
16:e1008488
Enterovirus A71 Oncolysis of Malignant Gliomas AuthorsXiaowei Zhang, Hanzhong Wang, Yuhan Sun, et al.
Journal Molecular Therapy (2020)
n/a:n/a
A bacterial artificial chromosome (BAC)-vectored noninfectious replicon of SARS-CoV-2 2 3 AuthorsYang Zhang, Wuhui Song, Shuiye Chen, et al.
Journal bioRxiv (2020)
n/a:2020.09.11.294330
Encapsulation of mrna into artificial viral capsids via hybridization of a β-annulus-dt20 conjugate and the poly(A) tail of mrna AuthorsYoko Nakamura, Yuki Sato, Hiroshi Inaba, et al.
Journal Applied Sciences (Switzerland) (2020)
10:1
N-glycosylation in the pre-membrane protein is essential for the Zika virus life cycle AuthorsYong Dae Gwon, Eva Zusinaite, Andres Merits, et al.
Journal Viruses (2020)
12:925
Antiviral activity of benzavir-2 against emerging flaviviruses AuthorsYong Dae Gwon, Mårten Strand, Richard Lindqvist, et al.
Journal Viruses (2020)
12:351
ANGPTL8 enhances insulin sensitivity by directly activating insulin-mediated AKT phosphorylation AuthorsZongli Zhang, Haiqing Wu, Longjun Dai, et al.
Journal Gene (2020)
749:144707
Direct RNA nanopore sequencing of full-length coronavirus genomes provides novel insights into structural variants and enables modification analysis AuthorsAdrian Viehweger, Sebastian Krautwurst, Kevin Lamkiewicz, et al.
Journal Genome Research (2019)
29:1545
DDX 3X and specific initiation factors modulate FMR1 repeat-associated non-AUG-initiated translation AuthorsAlexander Linsalata, Fang He, Ahmed Malik, et al.
Journal EMBO Reports (2019)
n/a:n/a
Structures of kobuviral and siciniviral polymerases reveal conserved mechanism of picornaviral polymerase activation AuthorsAnna Dubankova, Vladimira Horova, Martin Klima, et al.
Journal Journal of Structural Biology (2019)
n/a:n/a
Cell-fusing agent virus reduces arbovirus dissemination in Aedes aegypti mosquitoes in vivo AuthorsArtem Baidaliuk, Elliott Miot, Sebastian Lequime, et al.
Journal Journal of Virology (2019)
n/a:JVI
An Attenuated Zika Virus Encoding Non-Glycosylated Envelope (E) and Non-Structural Protein 1 (NS1) Confers Complete Protection against Lethal Challenge in a Mouse Model AuthorsArun Annamalai, Aryamav Pattnaik, Bikash Sahoo, et al.
Journal Vaccines (2019)
7:112
Regulation of HCV infection by Cellular Retinoic Acid Binding Proteins through the modulation of lipid droplet abundance AuthorsBo-Ram Bang, Meng Li, Kuen-Nan Tsai, et al.
Journal Journal of Virology (2019) JVI. 02302
Basal expression of interferon regulatory factor 1 drives intrinsic hepatocyte resistance to multiple RNA viruses AuthorsDaisuke Yamane, Hui Feng, Efrain E Rivera-Serrano, et al.
Journal Nature Microbiology (2019)
Basal expression of interferon regulatory factor 1 drives intrinsic hepatocyte resistance to multiple RNA viruses AuthorsDaisuke Yamane, Hui Feng, Efraín E Rivera-Serrano, et al.
Journal Nature Microbiology (2019)
4:1096
The ER Membrane Protein Complex Promotes Biogenesis of Dengue and Zika Virus Non-structural Multi-pass Transmembrane Proteins to Support Infection AuthorsDavid L Lin, Takamasa Inoue, Yu-Jie Chen, et al.
Journal Cell Reports (2019)
27:1666
The small GTPase RAB1B promotes antiviral innate immunity by interacting with TNF receptor-associated factor 3 (TRAF3) AuthorsDia Beachboard, Moonhee Park, Madhuvanthi Vijayan, et al.
Journal Journal of Biological Chemistry (2019)
294:jbc. RA119.007917
Cellular entry and uncoating of naked and quasi-enveloped human hepatoviruses AuthorsEfrain E Rivera-Serrano, Olga Gonzalez-Lopez, Anshuman Das, et al.
Journal eLife (2019)
8 Generation of iPSCs from Jaw Periosteal Cells Using Self-Replicating RNA AuthorsFelix Umrath, Heidrun Steinle, Marbod Weber, et al.
Journal International Journal of Molecular Sciences (2019)
20:1648
Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses AuthorsIvana Kurelac, Luisa Iommarini, Renaud Vatrinet, et al.
Journal Nature Communications (2019)
10:1
The obstacle course to the inner retina: hyaluronic acid-coated lipoplexes cross the vitreous but fail to overcome the inner limiting membrane AuthorsJoke Devoldere, Mike Wels, Karen Peynshaert, et al.
Journal European Journal of Pharmaceutics and Biopharmaceutics (2019)
In revisio:n/a
Correction of bleeding in experimental severe hemophilia A by systemic delivery of factor VIII-encoding mRNA AuthorsJules Russick, Sandrine Delignat, Peter Milanov, et al.
Journal Haematologica (2019)
n/a:haematol.2018.210583
Hepatitis Delta Antigen Regulates mRNA and Antigenome RNA Levels during Hepatitis Delta Virus Replication AuthorsKaneemozhe Harichandran, Yiran Shen, Susannah Stephenson Tsoris, et al.
Journal Journal of Virology (2019)
93 Induction of Selenoprotein P mRNA during Hepatitis C Virus Infection Inhibits RIG-I-Mediated Antiviral Immunity AuthorsKazuhisa Murai, Masao Honda, Takayoshi Shirasaki, et al.
Journal Cell Host and Microbe (2019)
25:588
RNA Helicase LGP2 Negatively Regulates RIG-I Signaling by Preventing TRIM25-Mediated Caspase Activation and Recruitment Domain Ubiquitination AuthorsKendra M Quicke, Kristin Y Kim, Curt M Horvath, et al.
Journal Journal of Interferon & Cytokine Research (2019)
39:669
West Nile Virus Infection Blocks Inflammatory Response and T Cell Costimulatory Capacity of Human Monocyte-Derived Dendritic Cells AuthorsMatthew G Zimmerman, James R Bowen, Circe E McDonald, et al.
Journal Journal of Virology (2019)
93:n/a
Product UsageProduct: TransIT®-mRNA Transfection KitCell Type: Monocyte dendritic cells (human)
Nucleic Acid: viral RNA
Application: Gene/Protein Expression
Repression of ferritin light chain translation by human eIF3 AuthorsMC Pulos-Holmes, DN Srole, ASY Lee, et al.
Journal bioRxiv (2019)
Repression of ferritin light chain translation by human eIF3 AuthorsMia C Pulos-Holmes, Daniel N Srole, Maria G Juarez, et al.
Journal eLife (2019)
8:n/a
Antiviral candidates for treating hepatitis E virus infection AuthorsNatalie E Netzler, Daniel Enosi Tuipulotu, Subhash G Vasudevan, et al.
Journal Antimicrobial Agents and Chemotherapy (2019)
63:e00003
Antiviral candidates for treating hepatitis E virus infection AuthorsNatalie E Netzler, Daniel Enosi Tuipulotu, Subhash G Vasudevan, et al.
Journal Antimicrobial Agents and Chemotherapy (2019)
Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques AuthorsNorbert Pardi, Celia C LaBranche, Guido Ferrari, et al.
Journal Molecular Therapy - Nucleic Acids (2019)
15:36
A novel druggable interprotomer pocket in the capsid of rhino-and enteroviruses AuthorsRana Abdelnabi, James Geraets, Yipeng Ma, et al.
Journal PLoS Biology (2019)
17:e3000281
Antiviral candidates against the hepatitis E virus (HEV) and their combinations inhibit HEV growth in in vitro AuthorsTakashi Nishiyama, Tominari Kobayashi, Suljid Jirintai, et al.
Journal Antiviral Research (2019)
n/a:104570
Screening of novel drugs for inhibiting hepatitis E virus replication AuthorsTakashi Nishiyama, Tominari Kobayashi, Suljid Jirintai, et al.
Journal Journal of Virological Methods (2019)
270:1
Genotype 5 Hepatitis E Virus Produced by a Reverse Genetics System Has the Potential for Zoonotic Infection AuthorsTian‐Cheng Li, Huimin Bai, Sayaka Yoshizaki, et al.
Journal Hepatology Communications (2019)
3:160
Effective and Rapid Generation of Functional Neutrophils from Induced Pluripotent Stem Cells Using ETV2-Modified mRNA AuthorsVera S Brok-Volchanskaya, David A Bennin, Kran Suknuntha, et al.
Journal Stem Cell Reports (2019)
13:1099
Product UsageProduct: TransIT®-mRNA Transfection KitCell Type: Induced pluripotent stem cells (iPSC)
Nucleic Acid: RNA
Application: Gene/Protein Expression
Convergent evolution in the mechanisms of ACBD3 recruitment to picornavirus replication sites AuthorsVladimira Horova, Heyrhyoung Lyoo, Bartosz Rozycki, et al.
Journal PLoS Pathogens (2019)
15:e1007962
CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation. AuthorsWeiwei Cheng, Shaopeng Wang, Zhe Zhang, et al.
Journal Neuron (2019)
n/a:n/a
HIV-1 Tat protein inhibits the hematopoietic support function of human bone marrow mesenchymal stem cells AuthorsYahong Yuan, Chunfang Zhou, Qi Yang, et al.
Journal Virus Research (2019)
n/a:197756
Dual role of the amphipathic helix of hepatitis C virus NS5A in the viral polyprotein cleavage and replicase assembly AuthorsYang Zhang, Xiaomin Zhao, Jingyi Zou, et al.
Journal Virology (2019)
n/a:n/a
TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA AuthorsYou Li, Li Wang, Efrain E Rivera-Serrano, et al.
Journal Nucleic Acids Research (2019)
TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA AuthorsYou Li, Li Wang, Efraín E Rivera-Serrano, et al.
Journal Nucleic Acids Research (2019)
47:6411
Cell-cell fusion induced by reovirus FAST proteins enhances replication and pathogenicity of non-enveloped dsRNA viruses AuthorsYuta Kanai, Takahiro Kawagishi, Yusuke Sakai, et al.
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15:e1007675
Nanopore direct RNA sequencing reveals modification in full-length coronavirus genomes AuthorsAdrian Viehweger, Sebastian Krautwurst, Kevin Lamkiewicz, et al.
Journal bioRxiv (2018) 483693
Prolonged engraftment of transplanted hepatocytes in the liver by transient pro-survival factor supplementation using ex vivo mRNA transfection AuthorsAkitsugu Matsui, Satoshi Uchida, Akimasa Hayashi, et al.
Journal Journal of Controlled Release (2018)
285:1
APOBEC3-mediated restriction of RNA virus replication AuthorsAleksandra Milewska, Eveline Kindler, Philip Vkovski, et al.
Journal Nature (2018)
8:5960
Synonymous nucleotide modification of the KCNH2 gene affects both mRNA characteristics and translation of the encoded hERG ion channel AuthorsAlexander C Bertalovitz, Marika L Osterbur Badhey, Thomas V Mcdonald
Journal Journal of Biological Chemistry (2018)
293:12120
Issues with the Specificity of Immunological Reagents for NLRP3: Implications for Age-related Macular Degeneration AuthorsCassandra Kosmidou, Nikolaos E Efstathiou, Mien V Hoang, et al.
Journal Scientific Reports (2018)
8:461
Acetylation of cytidine in mRNA promotes translation efficiency AuthorsDaniel Arango, David Sturgill, Najwa Alhusaini, et al.
Journal Cell (2018)
175:1872
MicroRNA-122 supports robust innate immunity in hepatocytes by suppressing STAT3 phosphorylation AuthorsHui Xu, Shi-Jun Xu, Shu-Juan Xie, et al.
Journal bioRxiv (2018) 250746
Multiple poliovirus-induced organelles suggested by comparison of spatiotemporal dynamics of membranous structures and phosphoinositides AuthorsHyung S Oh, Sravani Banerjee, David Aponte-Diaz, et al.
Journal PLoS Pathogens (2018)
14:e1007036
Unexpected Replication Boost by Simeprevir for Simeprevir-resistant Variants in Genotype 1a Hepatitis C Virus AuthorsKazuhisa Murai, Tetsuro Shimakami, Christoph Welsch, et al.
Journal Antimicrobial Agents and Chemotherapy (2018) AAC. 02601
Optimization of Synthetic mRNA for Highly Efficient Translation and its Application in the Generation of Endothelial and Hematopoietic Cells from Human and Primate Pluripotent Stem Cells AuthorsKran Suknuntha, Lihong Tao, Vera Brok-Volchanskaya, et al.
Journal Stem Cell Reviews and Reports (2018) 1
Combination Immunotherapy of MUC1 mRNA Nano-vaccine and CTLA-4 Blockade Effectively Inhibits Growth of Triple Negative Breast Cancer AuthorsLina Liu, Yuhua Wang, Lei Miao, et al.
Journal Molecular Therapy (2018)
26:45
Cancer-associated mRNAs regulated by the Helix-Loop-Helix motif of human EIF3A AuthorsMarina Volegova, Jamie Cate
Journal bioRxiv (2018) 354399
Rhinovirus 3C protease suppresses apoptosis and triggers caspase-independent cell death AuthorsMark Lotzerich, Pascal S Roulin, Karin Boucke, et al.
Journal Nature Cell Death and Disease (2018)
9:272
Orthogonal regulation of ferritin translation by human eIF3 and the iron response proteins AuthorsMia C Pulos, Daniel N Srole, David T Mcswiggen, et al.
Journal bioRxiv (2018) 316299
Impact of a Patient-Derived Hepatitis C Viral RNA Genome with a Mutated MicroRNA Binding Site AuthorsMiguel Mata, Steven Neben, Karim Majzoub, et al.
Journal bioRxiv (2018) 469841
Identification of the Intragenomic Promoter Controlling Hepatitis E Virus Subgenomic RNA Transcription AuthorsQiang Ding, Ila Nimgaonkar, Nicholas F Archer, et al.
Journal mBio (2018)
9:e00769
Heterochromatin-Encoded Satellite RNAs Induce Breast Cancer AuthorsQuan Zhu, Nien Hoong, Aaron Aslanian, et al.
Journal Molecular Cell (2018)
Hijacking of multiple phospholipid biosynthetic pathways and induction of membrane biogenesis by a picornaviral 3CD protein AuthorsSravani Banerjee, David Aponte-Diaz, Calvin Yeager, et al.
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14:e1007086
Structure of tick-borne encephalitis virus and its neutralization by a monoclonal antibody AuthorsTibor Fuzik, Petra Formanova, Daniel Ruzek, et al.
Journal Nature (2018)
9:436
An analysis of two open reading frames (ORF3 and ORF4) of rat hepatitis E virus genome using its infectious cDNA clones with mutations in ORF3 or ORF4 AuthorsTominari Kobayashi, Masaharu Takahashi, Suljid Jirintai, et al.
Journal Virus Research (2018)
249:16
Roles of the 5' untranslated region of non-primate hepacivirus in translation initiation and viral replication AuthorsTomohisa Tanaka, Teruhime Otoguro, Atsuya Yamashita, et al.
Journal Journal of Virology (2018) JVI. 01997
Vibrio vulnificus quorum-sensing molecule cyclo (Phe-Pro) inhibits RIG-I-mediated antiviral innate immunity AuthorsWooseong Lee, Seung-Hoon Lee, Minwoo Kim, et al.
Journal Nature (2018)
9:1606
Hepatitis C virus NS5A inhibitor daclatasvir allosterically impairs NS4B-involved protein-protein interactions within the viral replicase and disrupts the replicase quaternary structure in a replicase assembly surrogate system AuthorsYang Zhang, Jingyi Zou, Xiaomin Zhao, et al.
Journal bioRxiv (2018) 335273
Translation of dipeptide repeat proteins from the C9ORF72 expanded repeat is associated with cellular stress AuthorsYoshifumi Sonobe, Ghanashyam Ghadge, Katsuhisa Masaki, et al.
Journal Neurobiology of Disease (2018)
A "top-down" approach to actuate poly (amine-co-ester) terpolymers for potent and safe mRNA delivery AuthorsYuhang Jiang, Alice Gaudin, Junwei Zhang, et al.
Journal Biomaterials (2018)
Cell culture-adaptive mutations of NS5A affect replication of hepatitis C virus differentially depending on the viral genotypes AuthorsAeri Chung, Bora Jin, Kwang-Hyub Han, et al.
Journal Journal of Medical Virology (2017)
89:146
The LINK-A lncRNA interacts with PtdIns (3, 4, 5) P 3 to hyperactivate AKT and confer resistance to AKT inhibitors AuthorsAifu Lin, Qingsong Hu, Chunlai Li, et al.
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19:238
Zika virus encoding non-glycosylated envelope protein is attenuated and defective in neuroinvasion AuthorsArun S Annamalai, Aryamav Pattnaik, Bikash R Sahoo, et al.
Journal Journal of Virology (2017) JVI. 01348
Circulating and exosome-packaged hepatitis C single-stranded RNA induce monocyte differentiation via TLR7/8 to polarized macrophages and fibrocytes AuthorsBanishree Saha, Karen Kodys, Adeyinka Adejumo, et al.
Journal Journal of Immunology (2017) 1600797
Circulating and Exosome-Packaged Hepatitis C Single-Stranded RNA Induce Monocyte Differentiation via TLR7/8 to Polarized Macrophages and Fibrocytes AuthorsBanishree Saha, Karen Kodys, Adeyinka Adejumo, et al.
Journal Journal of Immunology (2017)
198:1974
Fine-tuning and autoregulation of the intestinal determinant and tumor suppressor homeobox gene CDX2 by alternative splicing AuthorsCamille Balbinot, Marie Vanier, Olivier Armant, et al.
Journal Cell Death and Differentiation (2017)
24:2173
VP1 residues around the five-fold axis of enterovirus A71 mediate heparan sulfate interaction AuthorsChee Wah Tan, I-Ching Sam, Vannajan Sanghiran Lee, et al.
Journal Virology (2017)
501:79
Dengue virus hijacks a noncanonical oxidoreductase function of a cellular oligosaccharyltransferase complex AuthorsDavid L Lin, Natalia A Cherepanova, Leonia Bozzacco, et al.
Journal mBio (2017)
8:e00939
Single-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome AuthorsFlorian Douam, Gabriela Hrebikova, Yentli E Soto Albrecht, et al.
Journal Nature (2017)
8:14781
A replication-competent foot-and-mouth disease virus expressing a luciferase reporter AuthorsFuquan Zhang, Eva Perez-Martin, Nick Juleff, et al.
Journal Journal of Virological Methods (2017)
247:38
Hypervariable domain of eastern equine encephalitis virus nsP3 redundantly utilizes multiple cellular proteins for replication complex assembly AuthorsIlya Frolov, Maryna Akhrymuk, James A Mobley, et al.
Journal Journal of Virology (2017) JVI. 00371
The A946T variant of the RNA sensor IFIH1 mediates an interferon program that limits viral infection but increases the risk for autoimmunity AuthorsJacquelyn A Gorman, Christian Hundhausen, John S Errett, et al.
Journal Nature Immunology (2017)
18:744
An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model AuthorsJasdave S Chahal, Tao Fang, Andrew W Woodham, et al.
Journal Nature (2017)
7:252
Preclinical and clinical demonstration of immunogenicity by mRNA vaccines against H10N8 and H7N9 influenza viruses AuthorsKapil Bahl, Joe J Senn, Olga Yuzhakov, et al.
Journal Molecular Therapy (2017)
25:1316
The Ebola virus VP35 protein binds viral immunostimulatory and host RNAs identified through deep sequencing AuthorsKari A Dilley, Alexander A Voorhies, Priya Luthra, et al.
Journal PLoS ONE (2017)
12:e0178717
RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response AuthorsKatelyn M Green, M Rebecca Glineburg, Michael G Kearse, et al.
Journal Nature (2017)
8:2005
Escape of tick-borne flavivirus from 2'-C-methylated nucleoside antivirals is mediated by a single conservative mutation in NS5 that has a dramatic effect on viral fitness AuthorsLudek Eyer, Hirofumi Kondo, Darina Zouharova, et al.
Journal Journal of Virology (2017) JVI. 01028
Non-encapsidated 5'copy-back defective-interfering genomes produced by recombinant measles viruses are recognized by RIG-I and LGP2 but not MDA5 AuthorsMarie Mura, Chantal Combredet, Valerie Najburg, et al.
Journal Journal of Virology (2017) JVI. 00643
Functional consequences of RNA 5'terminal deletions on coxsackievirus B3 RNA replication and ribonucleoprotein complex formation AuthorsNicolas Leveque, Magali Garcia, Alexis Bouin, et al.
Journal Journal of Virology (2017) JVI. 00423
Zika virus protection by a single low-dose nucleoside-modified mRNA vaccination AuthorsNorbert Pardi, Michael J Hogan, Rebecca S Pelc, et al.
Journal Nature (2017)
543:248
Hepatitis E virus ORF3 is a functional ion channel required for release of infectious particles AuthorsQiang Ding, Brigitte Heller, Juan M. V. Capuccino, et al.
Journal PNAS (2017)
114:1147
Design, synthesis, and evaluation of thiazolidine-2, 4-dione derivatives as a novel class of glutaminase inhibitors AuthorsTeng-Kuang Yeh, Ching-Chuan Kuo, Yue-Zhi Lee, et al.
Journal Journal of Medicinal Chemistry (2017)
60:5599
Hepatitis E virus persists in the presence of a type III interferon response AuthorsXin Yin, Xinlei Li, Charuta Ambardekar, et al.
Journal PLoS Pathogens (2017)
13:e1006417
New class of early-stage enterovirus inhibitors with a novel mechanism of action AuthorsYipeng Ma, Rana Abdelnabi, Leen Delang, et al.
Journal Antiviral Research (2017)
147:67
Discovery of a novel antiviral agent targeting the nonstructural protein 4 (nsP4) of chikungunya virus AuthorsYuji Wada, Yasuko Orba, Michihito Sasaki, et al.
Journal Virology (2017)
505:102
N1-methyl-pseudouridine in mRNA enhances translation through eIF2a-dependent and independent mechanisms by increasing ribosome density AuthorsYuri V Svitkin, Yi Min Cheng, Tirtha Chakraborty, et al.
Journal Nucleic Acids Research (2017)
45:6023
Aggregation of a hepatitis C virus replicase module induced by ablation of p97/VCP AuthorsZhigang Yi, Zhenghong Yuan
Journal Journal of General Virology (2017)
98:1667
Extracellular interactions between hepatitis C virus and secreted apolipoprotein E AuthorsZhihua Li, Yadong Li, Yanwei Bi, et al.
Journal Journal of Virology (2017) JVI. 02227
MicroRNA-Detargeted Mengovirus for Oncolytic Virotherapy AuthorsAutumn J. Ruiz, Elizabeth M. Hadac, Rebecca A. Nace, et al.
Journal J. Virology. (2016)
90:4078
Characterization of a Novel Orthomyxo-like Virus Causing Mass Die-Offs of Tilapia AuthorsEran Bacharach, Nischay Mishra, Thomas Briese, et al.
Journal mBio (2016)
7:e00431
Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose AuthorsJasdave S. Chahal, Omar F. Khan, Christopher L. Cooper, et al.
Journal PNAS (2016)
113:E4133
Oligomerization of the Sec7 domain Arf guanine nucleotide exchange factor GBF1 is dispensable for Golgi localization and function but regulates degradation AuthorsJay M. Bhatt, Ekaterina G. Viktorova, Theodore Busby, et al.
Journal American Journal of Physiology Cell Physiology (2016)
310:C456
Replication of Human Norovirus RNA in Mammalian Cells Reveals Lack of Interferon Response AuthorsLin Qu, Kosuke Murakami, James R. Broughman, et al.
Journal Journal of Virology (2016)
90:8906
A Universal Next-Generation Sequencing Protocol To Generate Noninfectious Barcoded cDNA Libraries from High-Containment RNA Viruses AuthorsLindsey A. Moser, Lisbeth Ramirez-Carvajal, Vinita Puri, et al.
Journal mSystems (2016)
1:e00039
Palmitoylation Strengthens Cholesterol-dependent Multimerization and Fusion Activity of Human Cytomegalovirus Glycoprotein B (gB) AuthorsMarco Patrone, Ana Sofia Coroadinha, Ana P. Teixeira, et al.
Journal J. Biol. Chem. (2016)
291:4711
Targeting Innate Immunity for Antiviral Therapy through Small Molecule Agonists of the RLR Pathway AuthorsSowmya Pattabhi, Courtney R. Wilkins, Ran Dong, et al.
Journal J. Virology. (2016)
90:2372
Affinity Purification of the Hepatitis C Virus Replicase Identifies Valosin-Containing Protein, a Member of the ATPases Associated with Diverse Cellular Activities Family, as an Active Virus Replication Modulator AuthorsZhigang Yi, Caiyun Fang, Jingyi Zou, et al.
Journal Journal of Virology (2016)
90:9953
OLA1, a Translational Regulator of p21, Maintains Optimal Cell Proliferation Necessary for Developmental Progression AuthorsZonghui Ding, Yue Liu, Valentina Rubio, et al.
Journal Molecular and Cellular Biology (2016)
36:2568
Pathogen-Associated Molecular Pattern Recognition of Hepatitis C Virus Transmitted/Founder Variants by RIG-I Is Dependent on U-Core Length AuthorsAlison Kell, Mark Stoddard, Hui Li, et al.
Journal J. Virology. (2015)
89:11056
Virion-Independent Transfer of Replication-Competent Hepatitis C Virus RNA between Permissive Cells AuthorsAndrea Longatti, Bryan Boyd, Francis V. Chisari, et al.
Journal J. Virology. (2015)
89:2956
Transmitted/Founder Hepatitis C Viruses Induce Cell-Type- and Genotype-Specific Differences in Innate Signaling within the Liver AuthorsAngela M. Mitchell, Amy E. L. Stone, Linling Cheng, et al.
Journal mBio (2015)
6:e02510
Functionally conserved architecture of hepatitis C virus RNA genomes AuthorsDavid M. Mauger, Michael Golden, Daisuke Yamane, et al.
Journal PNAS (2015)
112:3692
Cell-Specific Establishment of Poliovirus Resistance to an Inhibitor Targeting a Cellular Protein AuthorsEkaterina G. Viktorova, Jules Nchoutmboube, Lauren A. Ford-Siltz, et al.
Journal J. Virology. (2015)
89:4372
A Synthetic Porcine Reproductive and Respiratory Syndrome Virus Strain Confers Unprecedented Levels of Heterologous Protection AuthorsHiep L. X. Vu, Fangrui Ma, William W. Laegreid, et al.
Journal J. Virology. (2015)
89:12070
Novel RNA chaperone domain of RNA-binding protein La is regulated by AKT phosphorylation AuthorsJulia Kuehnert, Gunhild Sommer, Avery W. Zierk, et al.
Journal Nucleic Acids Research (2015)
43:581
Middle East Respiratory Syndrome Coronavirus nsp1 Inhibits Host Gene Expression by Selectively Targeting mRNAs Transcribed in the Nucleus while Sparing mRNAs of Cytoplasmic Origin AuthorsKumari G. Lokugamage, Krishna Narayanan, Keisuke Nakagawa, et al.
Journal J. Virology. (2015)
89:10970
The Lysine Residues within the Human Ribosomal Protein S17 Sequence Naturally Inserted into the Viral Nonstructural Protein of a Unique Strain of Hepatitis E Virus Are Important for Enhanced Virus Replication AuthorsScott P. Kenney, Xiang-Jin Meng
Journal J. Virology. (2015)
89:3793
Hepatitis C Virus Sensing by Human Trophoblasts Induces Innate Immune Responses and Recruitment of Maternal NK Cells: Potential Implications for Limiting Vertical Transmission AuthorsSilvia Giugliano, Margaret G. Petroff, Bryce D. Warren, et al.
Journal Journal of Immunology (2015)
195:3737
Divergent Requirement for a DNA Repair Enzyme during Enterovirus Infections AuthorsSonia Maciejewski, Joseph H. C. Nguyen, Fernando Gomez-Herreros, et al.
Journal mBio (2015)
7:e01931
YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1 AuthorsSyam Prakash Somasekharan, Amal El-Naggar, Gabriel Leprivier, et al.
Journal Journal of Cell Biology (2015)
208:913
Ebola Virus GP Gene Polyadenylation Versus RNA Editing AuthorsValentina A. Volchkova, Jaroslav Vorac, Laurie Repiquet-Paire, et al.
Journal Journal of Infectious Disease (2015)
212:S191
Dissecting the Roles of the 5' Exoribonucleases Xrn1 and Xrn2 in Restricting Hepatitis C Virus Replication AuthorsYou Li, Daisuke Yamane, Stanley M. Lemon
Journal J. Virology. (2015)
89:4857
Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells AuthorsAmy L. Firth, Carl T. Dargitz, Susan J. Qualls, et al.
Journal PNAS (2014)
111:E1723
Product UsageProduct: TransIT®-mRNA Transfection KitCell Type: Induced pluripotent stem cells (iPSC)
Nucleic Acid: mRNA
Application: Gene/Protein Expression
Hepatitis C Virus RNA Replication and Virus Particle Assembly Require Specific Dimerization of the NS4A Protein Transmembrane Domain AuthorsAndrew Kohlway, Nathan Pirakitikulr, Francisco N. Barrera, et al.
Journal J. Virology. (2014)
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Hepatitis C Virus Genotype 5a Subgenomic Replicons for Evaluation of Direct-Acting Antiviral Agents AuthorsConstance N. Wose Kinge, Christine Espiritu, Nishi Prabdial-Sing, et al.
Journal Antimicrobial Agents and Chemotherapy (2014)
58:5386
Expanding the Proteome of an RNA Virus by Phosphorylation of an Intrinsically Disordered Viral Protein AuthorsDaniel G. Cordek, Tayler J. Croom-Perez, Jungwook Hwang, et al.
Journal J. Biol. Chem. (2014)
289:24397
Novel antiviral host factor, TNK1, regulates IFN signaling through serine phosphorylation of STAT1 AuthorsEe Lyn Ooi, Stephanie T. Chan, Noell E. Cho, et al.
Journal PNAS (2014)
111:1909
Dimerization of Flavivirus NS4B Protein AuthorsJing Zou, Xuping Xie, Le Tian Lee, et al.
Journal J. Virology. (2014)
88:3379
A Critical Determinant of Neurological Disease Associated with Highly Pathogenic Tick-Borne Flavivirus in Mice AuthorsKentaro Yoshii, Yuji Sunden, Kana Yokozawa, et al.
Journal J. Virology. (2014)
88:5406
New Small-Molecule Inhibitors Effectively Blocking Picornavirus Replication AuthorsLauren A. Ford Siltz, Ekaterina G. Viktorova, Ben Zhang, et al.
Journal J. Virology. (2014)
88:11091
Development of a Gaussia Luciferase-Based Human Norovirus Protease Reporter System: Cell Type-Specific Profile of Norwalk Virus Protease Precursors and Evaluation of Inhibitors AuthorsLin Qu, Sompong Vongpunsawad, Robert L. Atmar, et al.
Journal J. Virology. (2014)
88:10312
Tick-borne flaviviruses alter membrane structure and replicate in dendrites of primary mouse neuronal cultures AuthorsMinato Hirano, Kentaro Yoshii, Mizuki Sakai, et al.
Journal Journal of General Virology (2014)
95:849
Variable region of the 3' UTR is a critical virulence factor in the Far-Eastern subtype of tick-borne encephalitis virus in a mouse model AuthorsMizuki Sakai, Kentaro Yoshii, Yuji Sunden, et al.
Journal Journal of General Virology (2014)
95:823
Novel Indole-2-Carboxamide Compounds Are Potent Broad-Spectrum Antivirals Active against Western Equine Encephalitis Virus In Vivo AuthorsPhillip C. Delekta, Craig J. Dobry, Janice A. Sindac, et al.
Journal J. Virology. (2014)
88:11199
Murine Leukemia Virus Uses NXF1 for Nuclear Export of Spliced and Unspliced Viral Transcripts AuthorsToshie Sakuma, Jaime I. Davila, Jessica A. Malcolm, et al.
Journal J. Virology. (2014)
88:4069
hnRNP L and NF90 Interact with Hepatitis C Virus 5'-Terminal Untranslated RNA and Promote Efficient Replication AuthorsYou Li, Takahiro Masaki, Tetsuro Shimakami, et al.
Journal J. Virology. (2014)
88:7199
Elevation of Receptor Tyrosine Kinases by Small Molecule AKT Inhibitors in Prostate Cancer Is Mediated by Pim-1 AuthorsBo Cen, et al.
Journal Cancer Research (2013)
73:3402
The Essential, Nonredundant Roles of RIG-I and MDA5 in Detecting and Controlling West Nile Virus Infection AuthorsJohn S. Errett, et al.
Journal Journal of Virology (2013)
87:11416
N-linked glycan in tick-borne encephalitis virus envelope protein affects viral secretion in mammalian cells, but not in tick cells AuthorsKentaro Yoshii, et al.
Journal Journal of General Virology (2013)
94:2249
Regulation of Hepatitis C Virus Replication by Nuclear Translocation of Nonstructural 5A Protein and Transcriptional Activation of Host Genes AuthorsMuhammad Ahmad Maqbool, et al.
Journal Journal of Virology (2013)
87:5523
Low Oxygen Tension Enhances Hepatitis C Virus Replication AuthorsN. Vassilaki, et al.
Journal Journal of Virology (2013)
87:2935
Competing and noncompeting activities of miR-122 and the 5' exonuclease Xrn1 in regulation of hepatitis C virus replication AuthorsYou Li, et al.
Journal PNAS (2013)
110:1881
The 3A Protein from Multiple Picornaviruses Utilizes the Golgi Adaptor Protein ACBD3 To Recruit PI4KIII{beta} AuthorsAlexander L. Greninger, Giselle M. Knudsen, Miguel Betegon, Alma L. Burlingame, Joseph L. DeRisi
Journal Journal of Virology (2012)
86:3605-3616
Severe Acute Respiratory Syndrome Coronavirus Protein nsp1 Is a Novel Eukaryotic Translation Inhibitor That Represses Multiple Steps of Translation Initiation AuthorsKumari G. Lokugamage, et al.
Journal Journal of Virology (2012)
86:13598
Aberrant expression of c-Jun in glioblastoma by internal ribosome entry site (IRES)-mediated translational activation AuthorsLior Blau, et al.
Journal PNAS (2012)
109:E2875
Ex Vivo and In Vivo Inhibition of Human Rhinovirus Replication by a New Pseudosubstrate of Viral 2A Protease AuthorsNisrine Falah, Sebastien Violot, Didier Decimo, Fatma Berri, Marie-Laure Foucault-Grunenwald, Theophile Ohlmann, Isabelle Schuffenecker, Florence Morfin, Bruno Lina, Beatrice Riteau, Jean-Claude Cortay
Journal Journal of Virology (2012)
86:691-704
Base Pairing between Hepatitis C Virus RNA and MicroRNA 122 3' of Its Seed Sequence Is Essential for Genome Stabilization and Production of Infectious Virus AuthorsTetsuro Shimakami, Daisuke Yamane, Christoph Welsch, Lucinda Hensley, Rohit K. Jangra, Stanley M. Lemon
Journal Journal of Virology (2012)
86:7372-7383
Severe Acute Respiratory Syndrome Coronavirus nsp1 Facilitates Efficient Propagation in Cells through a Specific Translational Shutoff of Host mRNA AuthorsTomohisa Tanaka, et al.
Journal Journal of Virology (2012)
86:11128
Alphacoronavirus Transmissible Gastroenteritis Virus nsp1 Protein Suppresses Protein Translation in Mammalian Cells and in Cell-Free HeLa Cell Extracts but Not in Rabbit Reticulocyte Lysate AuthorsCheng Huang, Kumari G. Lokugamage, Janet M. Rozovics, Krishna Narayanan, Bert L. Semler, Shinji Makino
Journal Journal of Virology (2011)
85:638-643
Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA AuthorsKatalin Kariko, Hiromi Muramatsu, Janos Ludwig, Drew Weissman
Journal Nucleic Acids Research (2011)
39(21):e142
Regulation of Infectious Genotype 1a Hepatitis C Virus Production by Domain III of NS5A AuthorsKim, Seungtaek Welsch, Christoph Yi, MinKyung Lemon, Stanley M
Journal Journal of Virology (2011)
85(13):6645-6656
Analysis of Poliovirus Protein 3A Interactions with Viral and Cellular Proteins in Infected Cells AuthorsNatalya L. Teterina, Yuval Pinto, Joseph D. Weaver, Kenneth S. Jensen, Ellie Ehrenfeld
Journal Journal of Virology (2011)
85:4284-4296
Regulation of the Production of Infectious Genotype 1a Hepatitis C Virus by NS5A Domain III AuthorsSeungtaek Kim, Christoph Welsch, MinKyung Yi, Stanley M. Lemon
Journal Journal of Virology (2011)
85:6645-6656
A PSAP motif in the ORF3 protein of hepatitis E virus is necessary for virion release from infected cells AuthorsShigeo Nagashima, Masaharu Takahashi, Jirintai, Toshinori Tanaka, Kentaro Yamada, Tsutomu Nishizawa, Hiroaki Okamoto
Journal Journal of General Virology (2011)
92:269-278
The Acidic Domain of Hepatitis C Virus NS4A Contributes to RNA Replication and Virus Particle Assembly AuthorsTung Phan, Andrew Kohlway, Peniel Dimberu, Anna Marie Pyle, Brett D. Lindenbach
Journal Journal of Virology (2011)
85:1193-1204
Rhesus Monkey Rhadinovirus ORF57 Induces gH and gL Glycoprotein Expression through Posttranscriptional Accumulation of Target mRNAs AuthorsYoung C. Shin, Ronald C. Desrosiers
Journal Journal of Virology (2011)
85:7810-7817
Innate immune suppression enables frequent transfection with RNA encoding reprogramming protein AuthorsAngel M, Yanik MF
Journal PLoS (2010)
5(7):e11756
Crimean-Congo Hemorrhagic Fever Virus-Encoded Ovarian Tumor Protease Activity Is Dispensable for Virus RNA Polymerase Function AuthorsEric Bergeron, Cesar G. Albarino, Marina L. Khristova, Stuart T. Nichol
Journal Journal of Virology (2010)
84:216-226
Viable Polioviruses That Encode 2A Proteins with Fluorescent Protein Tags AuthorsNatalya L. Teterina, Eric A. Levenson, Ellie Ehrenfeld
Journal Journal of Virology (2010)
84:1477-1488
Regulation of Hepatitis C Virus Translation and Infectious Virus Production by the MicroRNA miR-122 AuthorsRohit K. Jangra, MinKyung Yi, and Stanley M. Lemon
Journal Journal of Virology (2010)
84:6615-6625
Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRN AuthorsWarren L, Manos PD, Ahfeldt T, Loh YH, Li H, Lau F, Ebina W, Mandal PK, Smith ZD, Meissner A, Daley GQ, Brack AS, Collins JJ, Cowan C, Schlaeger TM, Rossi DJ
Journal Cell Stem Cell (2010)
7(5):618-630
Inhibition of mRNA export and dimerization of interferon regulatory factor 3 by Theiler's virus leader protein AuthorsCeline Ricour, Sophie Delhaye, Stanleyson V. Hato, Tamara D. Olenyik, Benedicte Michel, Frank J. M. van Kuppeveld, Kurt E. Gustin, Thomas Michiels
Journal Journal of General Virology (2009)
90:177
hnRNPs Relocalize to the Cytoplasm following Infection with Vesicular Stomatitis Virus AuthorsElizabeth L. Pettit Kneller, John H. Connor, Douglas S. Lyles
Journal Journal of Virology (2009)
83:770
cAMP-Dependent Posttranscriptional Regulation of Steroidogenic Acute Regulatory (STAR) Protein by the Zinc Finger Protein ZFP36L1/TIS11b AuthorsHaichuan Duan, Nadia Cherradi, Jean-Jacques Feige, Colin Jefcoate
Journal Molecular Endocrinology (2009)
23:497-509
ORF3 protein of hepatitis E virus is essential for virion release from infected cells AuthorsKentaro Yamada, Masaharu Takahashi, Yu Hoshino, Hideyuki Takahashi, Koji Ichiyama, Shigeo Nagashima, Toshinori Tanaka, Hiroaki Okamoto
Journal Journal of General Virology (2009)
90:1880-1891
Construction of an infectious cDNA clone of hepatitis E virus strain JE03-1760F that can propagate efficiently in cultured cells AuthorsKentaro Yamada, Masaharu Takahashi, Yu Hoshino, Hideyuki Takahashi, Koji Ichiyama, Toshinori Tanaka, Hiroaki Okamoto
Journal Journal of General Virology (2009)
90:457
Hepatitis C Virus NS2 Protein Contributes to Virus Particle Assembly via Opposing Epistatic Interactions with the E1-E2 Glycoprotein and NS3-NS4A Enzyme Complexes AuthorsTung Phan, Rudolf K. F. Beran, Christopher Peters, Ivo C. Lorenz, Brett D. Lindenbach
Journal Journal of Virology (2009)
83:8379-8395
Suppression of Host Gene Expression by Nsp1 Proteins of Group 2 Bat Coronaviruses AuthorsYukinobu Tohya, Krishna Narayanan, Wataru Kamitani, Cheng Huang, Kumari Lokugamage, Shinji Makino
Journal Journal of Virology (2009)
83(10):5282-5288
Recovery of Infectious Virus by Transfection of In Vitro-Generated RNA from Tulane Calicivirus cDNA AuthorsChao Wei, Tibor Farkas, Karol Sestak, Xi Jiang
Journal Journal of Virology (2008)
82:11429
In vitro expression of the HIV-2 genomic RNA is controlled by three distinct internal ribosome entry segments that are regulated by the HIV protease and the Gag polyprotein AuthorsEmiliano P. Ricci, Cecile H. Herbreteau, Didier Decimo, Andreas Schaupp, Siddhartha A. K. Datta, Alan Rein, Jean-Luc Darlix, Theophile Ohlmann
Journal RNA (2008)
14:1443
Severe Acute Respiratory Syndrome Coronavirus nsp1 Suppresses Host Gene Expression, Including That of Type I Interferon, in Infected Cells AuthorsKrishna Narayanan, Cheng Huang, Kumari Lokugamage, Wataru Kamitani, Tetsuro Ikegami, Chien-Te K. Tseng, Shinji Makino
Journal Journal of Virology (2008)
82:4471
Thiopurines inhibit bovine viral diarrhea virus production in a thiopurine methyltransferase-dependent manner AuthorsSpencer Hoover, Rob Striker
Journal Journal of General Virology (2008)
89:1000
New mRNAs Are Preferentially Translated during Vesicular Stomatitis Virus Infection AuthorsZackary W. Whitlow, John H. Connor, Douglas S. Lyles
Journal Journal of Virology (2008)
82:2286
Hijacking components of the cellular secretory pathway for replication of poliovirus RN AuthorsBelov, Altan-Bonnet, Kovtunovych, Jackson, Lippincott-Schwartz, and Ehrenfeld
Journal Journal of Virology (2007)
81:558-567
Activation of cellular Arf GTPases by poliovirus protein 3CD corelates with virus replicatio AuthorsBelov, Habbersett, Franko, and Ehrenfeld
Journal Journal of Virology (2007)
81:9259 - 9267
The predominant cAMP-stimulated 3.5 kb StAR mRNA contains specific sequence elements in the extended 3'UTR that confer high basal instabilit AuthorsDuan and Jefcoate
Journal Journal of Molecular Endocrinology (2007)
38:159-179
Selection of an optimal RNA transfection reagent and comparison to electroporation for the delivery of viral RN AuthorsGonzalez, Pfannes, Brazas, and Striker
Journal Journal of Virological Methods (2007)
145:14-21
The predominant cAMP-stimulated 3.5 kb StAR mRNA contains specific sequence elements in the extended 3'UTR that confer high basal instability AuthorsHaichuan Duan, Colin R. Jefcoate
Journal Journal of Molecular Endocrinology (2007)
38:159
The New mScript mRNA Production System – Efficient mRNA Transcription, Capping and Tailing for the Highest Yields of Active Protein AuthorsMeis and Meis
Journal EPICENTRE Forum (2007)
14(1):4-5
Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradatio AuthorsKamitani, Narayanan, Huang, Lokugamage, Ikegami, Ito, Kubo, and Makino
Journal PNAS (2006)
103:12885
Cap-dependent and hepatitis C virus internal ribosome entry site-mediated translation are modulated by phosphorylation of eIF2 under oxidative stres AuthorsMacCallum, Jack, Egan, McDermott, Elliott, and Chan
Journal Journal of General Virology (2006)
87:3251