Downregulation of PD‑L1 via amide analogues of brefelamide: Alternatives to antibody‑based cancer immunotherapy AuthorsJing Zhang, Osamu Yamada, Shinya Kida, et al.
Journal Experimental and Therapeutic Medicine (2020)
19:3150
Gut microbial bile acid metabolite skews macrophage polarization and contributes to high-fat diet-induced colonic inflammation AuthorsLingyu Wang, Zizhen Gong, Xiuyuan Zhang, et al.
Journal Gut Microbes (2020)
12:n/a
Long non-coding RNA gas5 and intestinal mmp2 and mmp9 expression: A translational study in pediatric patients with IBD AuthorsMarianna Lucafò, Letizia Pugnetti, Matteo Bramuzzo, et al.
Journal International Journal of Molecular Sciences (2019)
20:5280
TRPP2 dysfunction decreases ATP-evoked calcium, induces cell aggregation and stimulates proliferation in T lymphocytes AuthorsRiccardo Magistroni, Alessandra Mangolini, Sonia Guzzo, et al.
Journal BMC Nephrology (2019)
20:1
The splicing factor RBM25 controls MYC activity in acute myeloid leukemia AuthorsSachin Pundhir, Ying Ge, Bo Torben Porse, et al.
Journal Nature Communications (2019)
10
CRACR2a is a calcium-activated dynein adaptor protein that regulates endocytic traffic AuthorsYuxiao Wang, Walter Huynh, Taylor Skokan, et al.
Journal Journal of Cell Biology (2019)
218:1619
Short chain ceramides disrupt immunoreceptor signaling by inhibiting segregation of Lo from Ld Plasma membrane components AuthorsDavid Holowka, Kankanit Thanapuasuwan, Barbara Baird
Journal Biology Open (2018)
7:bio034702
Identifying noncoding risk variants using disease-relevant gene regulatory networks AuthorsLong Gao, Yasin Uzun, Peng Gao, et al.
Journal Nature (2018)
9:702
Self-recognition of an inducible host lncRNA by RIG-I feedback restricts innate immune response AuthorsMinghong Jiang, Shikun Zhang, Zongheng Yang, et al.
Journal Cell (2018)
173:906
Deoxycholic Acid-Mediated Sphingosine-1-Phosphate Receptor 2 Signaling Exacerbates DSS-Induced Colitis through Promoting Cathepsin B Release AuthorsShengnan Zhao, Zizhen Gong, Xixi Du, et al.
Journal Journal of Immunology Research (2018)
2018
Pinpointing recurrent proviral integration sites in new models for latent HIV-1 infection AuthorsUlrike C Lange, Julia K Bialek, Thomas Walther, et al.
Journal Virus Research (2018)
249:69
A new calcium-activated dynein adaptor protein, CRACR2a, regulates clathrin-independent endocytic traffic in T cells AuthorsYuxiao Wang, Walter Huynh, Taylor Skokan, et al.
Journal bioRxiv (2018) 354498
A new transcript in the TCRB locus unveils the human ortholog of the mouse pre-DB1 promoter AuthorsBernard Lethe, Sylvia Snauwaert, Orian Bricard, et al.
Journal Immunity, Inflammation and Disease (2017)
5:346
NF{kappa}B-Pim-1-Eomesodermin axis is critical for maintaining CD8 T-cell memory quality AuthorsKarin M. Knudson, Curtis J. Pritzl, Vikas Saxena, et al.
Journal PNAS (2017)
114:E1659
Targeted HIV-1 latency reversal using CRISPR/Cas9-derived transcriptional activator systems AuthorsJulia K Bialek, Gabor A Dunay, Maike Voges, et al.
Journal PLoS ONE (2016)
11:e0158294
Genome-wide association study of plasma resistin levels identified rs1423096 and rs10401670 as possible functional variants in the Japanese population AuthorsRyoichi Kawamura, Yasuharu Tabara, Akiko Tsukada, et al.
Journal Physiology Genomics (2016)
48:874
Deoxycholic acid triggers NLRP3 inflammasome activation and aggravates dss-induced colitis in mice AuthorsShengnan Zhao, Zizhen Gong, Jiefei Zhou, et al.
Journal Frontiers in Immunology (2016)
7:536
Deregulated KLF4 Expression in Myeloid Leukemias Alters Cell Proliferation and Differentiation through MicroRNA and Gene Targets AuthorsValerie A. Morris, Carrie L. Cummings, Brendan Korb, et al.
Journal Molecular and Cellular Biology (2016)
36:559
Chenodeoxycholic acid activates NLRP3 inflammasome and contributes to cholestatic liver fibrosis AuthorsZizhen Gong, Jiefei Zhou, Shengnan Zhao, et al.
Journal Oncotarget (2016)
7:83951
SIRT1 deacetylates ROR{gamma}t and enhances Th17 cell generation AuthorsHyung W. Lim, Seung Goo Kang, Jae Kyu Ryu, et al.
Journal Journal of Experimental Medicine (2015)
212:607
H3K27 Demethylation at the Proviral Promoter Sensitizes Latent HIV to the Effects of Vorinostat in Ex Vivo Cultures of Resting CD4+ T Cells AuthorsManoj K. Tripathy, Mary E. M. Mcmanamy, Brandon D. Burch, et al.
Journal J. Virology. (2015)
89:8392
Stress-induced ceramide generation and apoptosis via the phosphorylation and activation of nSMase1 by JNK signaling AuthorsT Yabu, H Shiba, Y Shibasaki, et al.
Journal Cell Death and Differentiation (2015)
22:258
Differential 12-O-T etradecanoylphorbol-13-acetate-induced activation of rat mammary carcinoma susceptibility Fbxo10 variant promoters via a PKC-AP 1 pathway AuthorsXin Xu, Russell A Prough, David J Samuelson
Journal Molecular Carcinogenesis (2015)
54:134
A Silencer-Proximal Intronic Region Is Required for Sustained CD4 Expression in Postselection Thymocytes AuthorsDavid M. Henson, Chun Chou, Nagisa Sakurai, et al.
Journal Journal of Immunology (2014)
192:4620
ORMDL3 modulates store-operated calcium entry and lymphocyte activation AuthorsAmado Carreras-Sureda, et al.
Journal Human Molecular Genetics (2013)
22:519
Ets-1 Is Required for the Activation of VEGFR3 during Latent Kaposi's Sarcoma-Associated Herpesvirus Infection of Endothelial Cells AuthorsKimberley D. Gutierrez, et al.
Journal Journal of Virology (2013)
87:6758
Adenylyl Cyclase 6 Activation Negatively Regulates TLR4 Signaling through Lipid Raft-Mediated Endocytosis AuthorsWei Cai, et al.
Journal Journal of Immunology (2013)
191:6093
Role of O-Glycosylation and Expression of CD43 and CD45 on the Surfaces of Effector T Cells in Human T Cell Leukemia Virus Type 1 Cell-to-Cell Infection AuthorsDmitriy Mazurov, Anna Ilinskaya, Gisela Heidecker, Alexander Filatov
Journal Journal of Virology (2012)
86:2447-2458
Opposing Effects of a Tyrosine-Based Sorting Motif and a PDZ-Binding Motif Regulate Human T-Lymphotropic Virus Type 1 Envelope Trafficking AuthorsAnna Ilinskaya, Gisela Heidecker, David Derse
Journal Journal of Virology (2010)
84:6995-7004
Consensus motif for integrin transmembrane helix association AuthorsBryan W. Berger, Daniel W. Kulp, Lisa M. Span, Jessica L. DeGrado, Paul C. Billings, Alessandro Senes, Joel S. Bennett, William F. DeGrado
Journal PNAS (2010)
107:703-708
The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress AuthorsGerard Cantero-Recasens, Cesar Fandos, Fanny Rubio-Moscardo, Miguel A. Valverde, Ruben Vicente
Journal Human Molecular Genetics (2010)
19:111-121
T Cell Activation Leads to Protein Kinase C{theta}-Dependent Inhibition of TGF-{beta} Signaling AuthorsMartin Giroux, Jean-Sebastien Delisle, Alan O'Brien, Marie-Josee Hebert, Claude Perreault
Journal Journal of Immunology (2010)
185:1568-1576
Human CD1D Gene Expression Is Regulated by LEF-1 through Distal Promoter Regulatory Elements AuthorsQiao-Yi Chen, Tao Zhang, Seth H. Pincus, Shixiu Wu, David Ricks, Donald Liu, Zhongsheng Sun, Noel Maclaren, Michael S. Lan
Journal Journal of Immunology (2010)
184:5047-5054
Promoter Cloning and Characterization of the Anti-vascular Proliferation Gene, R-ras: ROLE OF ETS- AND SP-BINDING MOTIFS AuthorsLusheng Xu, Masanobu Komatsu
Journal Journal of Biological Chemistry (2009)
284:2706
Pyrin Critical to Macrophage IL-1{beta} Response to Francisella Challenge AuthorsMikhail A. Gavrilin, Srabani Mitra, Sudarshan Seshadri, Jyotsna Nateri, Freweine Berhe, Mark W. Hall, Mark D. Wewers
Journal Journal of Immunology (2009)
182:7982-7989
15-Deoxy-{Delta}12,14-prostaglandin J2 inhibits HIV-1 transactivating protein, Tat, through covalent modification AuthorsParisa Kalantari, Vivek Narayan, Andrew J. Henderson, K. Sandeep Prabhu
Journal FASEB (2009)
23(8):2366-2373
Cyclin-Dependent Kinase Inhibitors Block Leukocyte Adhesion and Migration AuthorsLi Liu, Barbara Schwartz, Yoshiaki Tsubota, Elaine Raines, Hiroaki Kiyokawa, Karyn Yonekawa, John M. Harlan, Lynn M. Schnapp
Journal Journal of Immunology (2008)
180:1808
Thioredoxin Reductase-1 Negatively Regulates HIV-1 Transactivating Protein Tat-dependent Transcription in Human Macrophages AuthorsParisa Kalantari, Vivek Narayan, Sathish K. Natarajan, Kambadur Muralidhar, Ujjawal H. Gandhi, Hema Vunta, Andrew J. Henderson, K. Sandeep Prabhu
Journal Journal of Biological Chemistry (2008)
283:33183
Persistent Activation of STAT3 by Latent Kaposi's Sarcoma-Associated Herpesvirus Infection of Endothelial Cells AuthorsAlmira S. Punjabi, Patrick A. Carroll, Lei Chen, Michael Lagunoff
Journal Journal of Virology (2007)
81:2449
The Homeobox Gene GAX Activates p21WAF1/CIP1 Expression in Vascular Endothelial Cells through Direct Interaction with Upstream AT-rich Sequence AuthorsChen, Leal, Patel, and Gorski
Journal Journal of Biological Chemistry (2007)
282:507-517
Allele-Specific Binding of CTCF to the Multipartite Imprinting Control Region KvDMR1 AuthorsFitzpatrick, Pugacheva, Shin, Abdullaev, Yang, Khatod, Lobanenkov, and Higgins
Journal Molecular and Cellular Biology (2007)
27:2636-2647
c-Myc and Sp1 Contribute to Proviral Latency by Recruiting Histone Deacetylase 1 to the Human Immunodeficiency Virus Type 1 Promoter AuthorsGuochun Jiang, Amy Espeseth, Daria J. Hazuda, David M. Margolis
Journal Journal of Virology (2007)
81:10914
c-Myc and Sp1 Contribute to Proviral Latency by Recruiting HDAC1 to the Human Immunodeficiency Virus Type 1 promote AuthorsJiang, Espeseth, Hazuda, and Margolis
Journal Journal of Virology (2007)
81(20):10914-10923
Persistent Activation of STAT3 by Latent Kaposi's Sarcoma-Associated Herpesvirus Infection of Endothelial Cell AuthorsPunjabi, Carroll, Chen, and Lagunoff
Journal Journal of Virology (2007)
81:2449-2458
The Homeobox Gene GAX Activates p21WAF1/CIP1 Expression in Vascular Endothelial Cells through Direct Interaction with Upstream AT-rich Sequences AuthorsYun Chen, Alejandro D. Leal, Sejal Patel, David H. Gorski
Journal Journal of Biological Chemistry (2007)
282:507
Flagellin Contamination of Recombinant Heat Shock Protein 70 Is Responsible for Its Activity on T Cells AuthorsZhiyong Ye, Yunn-Hwen Gan
Journal Journal of Biological Chemistry (2007)
282:4479
Latent Kaposi's Sarcoma-Associated Herpesvirus Infection of Endothelial Cells Activates Hypoxia-Induced Factor AuthorsCarroll, Kenerson, Yeung, and Lagunoff
Journal Journal of Virology (2006)
80:10802
Phosphorylated FADD induces NF-{kappa}B, perturbs cell cycle, and is associated with poor outcome in lung adenocarcinomas AuthorsChen, Bhojani, Heaford, Chang, Laxman, Thomas, Griffin, Yu, Coppola, Giordano, Lin, Adams, Orringer, Ross, Beer, Rehemtulla
Journal PNAS (2005)
102:12507-12512
The Homeobox Gene Gax Inhibits Angiogenesis through Inhibition of Nuclear Factor-{kappa}B-Dependent Endothelial Cell Gene Expression AuthorsPatel, Leal, Gorski
Journal Cancer Research (2005)
65:1414-1424
The Homeobox Protein MSX2 Interacts with Tax Oncoproteins and Represses Their Transactivation Activity AuthorsTwizere, Lefebvre, Collete, Debacq, Urbain, Heremans, Jauniaux, Burny, Willems, Kettmann
Journal Journal of Biological Chemistry (2005)
280:29804-29811
p38{alpha}, but not p38{beta}, inhibits the phosphorylation and presence of c-FLIPS in DISC to potentiate Fas-mediated caspase-8 activation and type I apoptotic signaling AuthorsTourian, Zhao, Srikant
Journal Journal of Cell Science (2004)
117:6459-6471