See what others are saying about TransIT®-LT1 Transfection Reagent...
"I recently tested TransIT®-2020 and TransIT®-LT1, and both reagents worked well in terms of their efficiency at transfecting human-derived iPS cells with CRISPR constructs and a fluorescent protein reporter. Through visual inspection, transfection efficiencies with TransIT®-2020 and TransIT®-LT1 were clearly higher than with Lipofectamine® 3000."
- Fedir Kiskin, University of Cambridge
"We routinely use Mirus TransIT®-LT1 Transfection Reagent for the delivery of plasmid DNA to carry out immunoprecipitation experiments. Our lab recently published using TransIT®-LT1 for this application to reveal a crucial regulator (MCUR1) for calcium uptake in the mitochondria to regulate cellular metabolism." (Mallilankaraman, K et al. Nature Cell Biology. December 2012).
- Dr. Karthik Mallilankaraman, Madesh Lab, Temple University
"Our lab is interested in identifying barriers to influenza virus cross-species transmission and how those control the emergence of new pandemic viruses...we were able to use TransIT®-LT1 in our studies to further implicate the viral polymerase complex as a major regulator of viral tropism and identify new adaptive strategies used by influenza as it moves from birds to people. Details of these efforts can be found in the Journal of Virology (Mehle, A et al. Journal of Virology. Feb 2012.)"
- Dr. Andrew Mehle, University of Wisconsin - Madison
"Our lab regularly transfects head and neck cancer squamous carcinoma cell lines as well as pre-cancerous oral lesion cell lines and primary cells with Mirus Bio products. We recently published a paper using Mirus Bio TransIT®-LT1 in which we concluded tobacco carcinogens up-regulate AP-1 activity and AP-1 dependent IL-8 and VEGF gene expression in head and neck cancer." (Swenson, W et al. Molecular Carcinogenesis. April 2011)
- Beverly Wuertz, Ondrey Lab, University of Minnesota