Label IT® Nucleic Acid Labeling Reagents

Efficient, direct, non-enzymatic labeling of DNA and RNA

  Product No. Quantity Price Add to Cart
Label IT® Nucleic Acid Labeling Kit, Biotin
  MIR 3425 labels 25 µg nucleic acid $213.00
  MIR 3400 labels 100 µg nucleic acid $533.00
Label IT® Nucleic Acid Labeling Kit, CX-Rhodamine
  MIR 3125 labels 25 µg nucleic acid $213.00
  MIR 3100 labels 100 µg nucleic acid $533.00
Label IT® Nucleic Acid Labeling Kit, Cy®3
  MIR 3625 labels 25 µg nucleic acid $252.00
  MIR 3600 labels 100 µg nucleic acid $629.00
Label IT® Nucleic Acid Labeling Kit, Cy®5
  MIR 3725 labels 25 µg nucleic acid $252.00
  MIR 3700 labels 100 µg nucleic acid $629.00
Label IT® Nucleic Acid Labeling Kit, Digoxin
  MIR 3325 labels 25 µg nucleic acid $213.00
  MIR 3300 labels 100 µg nucleic acid $533.00
Label IT® Nucleic Acid Labeling Kit, DNP
  MIR 3825 labels 25 µg nucleic acid $213.00
  MIR 3800 labels 100 µg nucleic acid $533.00
Label IT® Nucleic Acid Labeling Kit, Fluorescein
  MIR 3225 labels 25 µg nucleic acid $213.00
  MIR 3200 labels 100 µg nucleic acid $533.00
Label IT® Nucleic Acid Labeling Kit, TM-Rhodamine
  MIR 4125 labels 25 µg nucleic acid $213.00
  MIR 4100 labels 100 µg nucleic acid $533.00

Product Overview

  • Label Any DNA or RNA Template  Suitable for a wide range of applications
  • One-step Chemical Method – Easily and consistently control the labeling reactions
  • Adjustable Labeling Density – Achieve high sensitivity with optimally labeled DNA and RNA
  • Covalent Mechanism – Permanent, non-destructive modification of nucleic acid residues is ideal for many diverse applications; labels do not impact hybridization performance

Kit Components:
Each Kit contains a Label IT® Reagent, Label IT® Reconstitution Solution, 10X Labeling Buffer and solutions.

NOTE: All the Label IT® Reagents use the same technology, but each attach different fluorophores with distinct excitation and emission spectra.

A Novel Electrophoresis System uses Label IT® -Fluorescein for Ethidium Bromide Free Labeling of DNA Markers
Learn more about the BluePippin™ system...

Figures and Data

Label IT Nucleic Acid Labeling Kits

Label IT® Nucleic Acid Labeling Kits. The Label IT® chemical labeling reagents are composed of three regions: the label (fluorophore or hapten) (green), the linker (yellow) which facilitates electrostatic interactions with nucleic acids and the reactive alkylating group (blue) that covalently attaches the Label IT® reagent to any reactive heteroatom within the nucleic acids. Attachment of the Label IT® Reagents to nucleic acids does not alter the structure of the nucleic acid or affect downstream hybridization performance, and as such, nucleic acids labeled using the Label IT® Reagents can be employed in multiple applications as defined by the researcher.

Non-destructive Direct Labeling of Nucleic Acid

Non-destructive Direct Labeling of Nucleic Acid. Mouse total RNA was labeled with Label IT® Cy®3 (B) electrophoresed and analyzed alongside unlabeled total RNA (A) on an Agilent RNA 6000 Nano chip. RNA Integrity Number (RIN) is approximately 9.0 for both labeled and unlabeled samples.

Generation of Sensitive FISH Probes

Generation of Sensitive FISH Probes. Multicolor chromosome PAINT analysis using Label IT® Biotin labeled human chromosome 7 (Streptavidin-Cy®3 conjugate detection) and Label IT® Fluorescein labeled human chromosome 6 on a Jurkat metaphase spread, with DAPI stained chromosomes in blue.

Product Resources

Specifications

Storage Conditions:
All Configurations: Store the Label IT® Reagent at -20°C in both dried pellet and reconstituted form. Store all other supplied reagents at -20°C. Store G50 microspin purification columns at 4°C. DO NOT FREEZE.

Product Guarantee:
All Configurations: 1 year (6 months after reconstitution)

Technical Product Literature


Additional Resources

COA Lookup

Download Certificates of Analysis

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