Mirus Bio Phosphatase Inhibitor Cocktail provides the following features and benefits:
- Convenient – Optimized formulation suitable for cell and tissue extracts
- High Activity – Effectively protects phosphoproteins from phosphatases present in cell lysates
- Broad Spectrum – Inhibits serine/threonine phosphatases and protein tyrosine phosphatases
Phosphorylation/dephosphorylation state serves as a molecular switch that controls diverse biological processes. The ability to preserve protein phosphorylation during cell lysis and protein purification is critical to studying the biological role of phosphorylation state on target molecules.
Mirus Phosphatase Inhibitor Cocktail contains an optimized combination of four broad spectrum phosphatase inhibitors (sodium fluoride, sodium orthovanadate, sodium pyrophosphate and β-glycerophosphate) that protect target proteins from dephosphorylation by serine/threonine phosphatases and protein tyrosine phosphatases.