Protease Inhibitor Cocktail
For mammalian cell and tissue extracts
- Convenient – Ready-to-use solution
- High Activity – Optimized formulation for mammalian cell extracts
- Broad Spectrum – Provides complete protection during protein isolation
- Compatible – Available in animal-origin-free format
Cell lysis releases endogenous proteases into the cell extract where they are available to degrade proteins present in the lysate. During protein purification, it is critical to protect your protein of interest against uncontrolled proteolysis caused by proteases present in cell and tissue extracts.
The addition of protease inhibitors to cell lysis and protein purification buffers improves the yield of intact, active target proteins by protecting your protein of interest against degradation by cellular proteases. Mirus Protease Inhibitor Cocktail is an optimized formulation of inhibitors (AEBSF, Aprotinin, Bestatin, E-64, Leupeptin, and Pepstatin A ) selected for their ability to inhibit proteases known to be present in mammalian cell extracts.