Current FDA Approved Cell & Gene Therapies
Let’s ring in the new year with a list of all current FDA approved cell and gene therapies to date!
Read on to learn more about the 34 different treatments and cures.
Search Results for: TransIt-Virusgen GMP – Page 2
How can I increase my viral titers and improve the percentage of full AAVs?
In today’s TransMission, we answer the FAQ: “How can I increase my viral titers and improve the percentage of full AAVs?”
AAV Production Case Study
Case study on how to build an AAV production platform with higher titers and higher percent full capsids
FAQs | Virus Production
Frequently Asked Questions | Virus Production flashBAC Baculovirus Expression TransIT-Lentivirus System TransIT-Lenti Transfection TransIT-VirusGEN Transfection VirusGEN AAV Transfection VirusGEN LV Transfection flashBAC™ Baculovirus Expression Systems
Transfecting Insect Cells, Pt. 4
Howdy everyone! What we have all BEEn waiting for: the final installment of our ‘Transfecting Insect Cells’ series with Dr. Bees.
So far, we have discussed common insect cell lines and TransIT®-Insect (Part 1), producing baculovirus with flashBAC™ (Part 2) and key features of pOET Transfer Plasmids (Part 3). Today in Part 4, we will bug out on how baculovirus can be used to produce virus-like particles (VLPs) and other kinds of viral vectors, such as AAV!
Understand Viral Titer & Quality
The cell and gene therapy field has burgeoned in the last decade with drug candidate treatments for many different diseases. Determining the correct patient dosage has become more important than ever to extend the reach of the multi-million-dollar manufacturing runs required to generate these viral therapies.
Genome copies (GC), capsids, GC/capsid ratios, percent full, functional titering… what does it all mean? In this Transfection 101, we summarize commonly used approaches to verify that manufactured viral vectors are of high quality and functionality, appropriate for use in patients.