Protein Production
Recombinant protein and mAb production Get the titer you need from your cell line of choice We’ve designed an advanced transfection solution for industry-leading protein
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Crossing the BBB with Nanobodies
The blood brain barrier (BBB) protects our brains from circulating pathogens and inflammatory cells. However, it also prevents the delivery of therapeutics into the brain. In this SNiP, we highlight a study from Rué et al. that describes a bispecific nanobody construct that can bind an Alzheimer’s disease target as well as a receptor at the BBB interface to promote entry into the brain.
Transfecting Insect Cells, Pt. 4
Howdy everyone! What we have all BEEn waiting for: the final installment of our ‘Transfecting Insect Cells’ series with Dr. Bees.
So far, we have discussed common insect cell lines and TransIT®-Insect (Part 1), producing baculovirus with flashBAC™ (Part 2) and key features of pOET Transfer Plasmids (Part 3). Today in Part 4, we will bug out on how baculovirus can be used to produce virus-like particles (VLPs) and other kinds of viral vectors, such as AAV!
Storage of TransITs
Proper storage and handling of TransIT® reagents are required to maintain optimal transfection performance. This is a quick reference page for storage and handling of Mirus TransIT® Transfection Reagents and Kits.