Mirus Announces Transfection Advance: TransIT-X2® Dynamic Delivery System
New High Performance Broad Spectrum Transfection System, Capable of Delivering DNA and siRNA
[Madison, WI July 31, 2013] Mirus Bio has expanded its transfection expertise with the development of the TransIT-X2® Dynamic Delivery System, an innovative polymeric system for high efficiency nucleic acid delivery. TransIT-X2® can be used for independent or simultaneous delivery of DNA and siRNA. The TransIT-X2® Dynamic Delivery System offers researchers:
- Efficiency—Exceptional broad spectrum transfection
- Versatility—Cutting edge delivery of plasmid DNA and/or siRNA
- Technology—Novel non-liposomal polymeric delivery
“Profound advances in gene delivery technology have been lacking for some time,” said Scott Hayes, Vice President, Mirus Bio LLC. “As a result, researchers have increasingly resorted to virus-borne or physical disruption technologies to facilitate nucleic acid uptake in difficult-to-transfect cell types despite inherent limitations with each of these methods. A better understanding of the barriers to transfection, and ways to overcome them, has led to the development of a new innovative polymeric dynamic delivery system. This system provides superior delivery of plasmid DNA and siRNA into a vast array of cell types. We feel that this technology provides distinct advantages over other means of transfection and opens new avenues for experimental design.”
In head-to-head testing, TransIT-X2® outperformed the market leader by at least 2-fold in cell types that include: A549, CHO-K1, Hep G2, HCC1143, HUVEC, LNCaP, MDA-MB-468, MDCK, HMEC, Immortalized Keratinocytes and T47D.
For experimental details and testing results, please visit www.TheTransfectionExperts.com