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Hijacking Viruses: Optimizing Lentivirus-based Cell Engineering

Researcher at Harvard Overcomes Challenges with Lentivirus

Researchers commonly employ lentiviruses to modify cells genetically. However, they must overcome several challenges when using these viruses in the laboratory or clinic.

Fill out the form to listen to the latest LabTalk Podcast produced by The Scientist, where Filippo Rossignoli, instructor in neurosurgery at the Center for Stem Cell and Translational Immunotherapy at Brigham and Women’s Hospital and Harvard Medical School, discusses using lentiviruses to engineer cell therapies and the troubleshooting process he undertook to optimize viral production and infection.