CRISPR’ing Wheat with a Gene Gun

What happens when chemical transfection meets gene guns? In today’s Small News in Pieces (SNiP), we highlight biolistic transfection and a study that incorporated TransIT®-2020 Transfection Reagent to genetically modify wheat plants.

Peering into the Proteome of SMA

SNiP-ing a recent study related to Spinal Muscular Atrophy (SMA). Digest this SNiP to learn about SMA and the proteomic analysis conducted by Brown et al. to identify biomarkers and determinants of SMA severity.

Leveraging Avian AAV in Pekin Duck Research

Though typically seen in reference to human disease, AAV has applications apart from therapeutics for otherwise untreatable maladies. Today we SNiP a proof-of-concept study that features a unique use for TransIT-VirusGEN® in production of avian AAV for the transduction of Pekin duck cells in vitro and in vivo.

SNiP-ing Success with CRISPR

It’s fitting that we SNiP (Small News in Pieces) an article about CRISPR. Read on if you think your CRISPR experiments are plagued by re-cutting, which can decrease gene-editing efficiency and introduce undesired mutations. Co-transfection with hideRNA may be a quick fix!

Tell Me More About Telomeres

Today’s TransMission is a SNiP (Small News in Pieces). Read how Jack et al. use TransIT® and Label IT® to study telomeres.

From AAV to TAZ

Today’s TransMission is a SNiP (Small News in Pieces). Read how Hwang et al. use AAV to study mitochondrial biogenesis.