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Genome Editing Research

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TransIT-X2® Dynamic Delivery System

A novel, polymeric system for delivery of multiple nucleic acids to mammalian cells. Delivers CRISPR/Cas9 components in the following formats:

• DNA – Deliver plasmid DNA expressing Cas9 or guide RNA
• Guide RNA – Deliver guide RNA oligonucleotides targeting your gene of interest
• RNP – Deliver Cas9/guide RNA ribonucleoprotein complexes

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TransIT®-mRNA Transfection Kit

A high efficiency, low toxicity transfection reagent for mammalian cells. Delivers CRISPR/Cas9 components in the following formats:

• mRNA – Deliver messenger RNA expressing Cas9
• Guide RNA – Deliver guide RNA targeting your gene of interest

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Ingenio® Electroporation Solution

A high efficiency electroporation solution compatible with most conventional electroporation devices including Lonza-Amaxa®, Bio-Rad® or Harvard BTX®. Delivers CRISPR/Cas9 components in the following formats:

• DNA – Deliver plasmid DNA expressing Cas9 or guide RNA
• mRNA – Deliver messenger RNA expressing Cas9
• Guide RNA – Deliver guide RNA oligonucleotides targeting your gene of interest
• RNP – Deliver Cas9/guide RNA ribonucleoprotein complexes

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Brochure: CRISPR/Cas9 Genome Editing
Poster: Optimization of DNA, RNA and RNP Delivery Methods for Efficient CRISPR/Cas9 Mediated Cell Engineering