Search Results for: TransIt-Virusgen transfection reagent

VirusGEN® and RoosterGEM™, a match made for GMP mRNA transfection

Here we highlight some of the exciting results from Mirus’ ongoing collaboration with RoosterBio. Earlier this year, RoosterBio presented a poster at ASGCT and ISCT which showcased using TransIT-VirusGEN® for high-efficiency transfection of mRNA into human mesenchymal stromal cells (hMSCs) cultured in RoosterGEM™ medium. Both VirusGEN® and RoosterGEM™ have GMP formulations available, which allows for rapid implementation into clinical manufacturing processes that require highly qualified reagents.

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Transfection Efficiency

“How successful was your transfection experiment?” Transfection efficiency is a measure used to answer this question. Because success can be defined in multiple ways, how to calculate transfection efficiency will depend on the type of transfection experiment.

In this TransMission Transfection 101 we will cover: the many meanings of transfection efficiency, common reporter assays to measure transfection efficiency, and how to improve transfection efficiency.

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AAV Manufacturing

Harnessing recombinant adeno-associated virus (AAV) as vectors for cell and gene therapy requires robust upstream manufacturing processes that are reproducible, scalable, and quality-controlled. By combining purpose-built polymers and lipids, Mirus Bio has developed animal origin free reagents that seamlessly blend into the AAV manufacturing process at the time of transfection to dramatically increase AAV titers.

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