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Why Replace FuGENE 6? FREE Sample Data Comparison Protocol Comparison Data Product Details
 

The Proof is in the Performance

Comparable Luciferase Expression In Side-by-Side Transfections

Figure 1

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The indicated cell lines were transfected in duplicate with 1 µg of a luciferase expression vector per well of a 12-well plate using either 3 µl of the TransIT®-LT1 or FuGENE® 6 Reagents. Cells were harvested 24 hours post-transfection and assayed for luciferase activity.

The TransIT®-LT1 Protocol Results in Greater Gene Expression

The TransIT®-LT1 and FuGENE® 6 Protocols Recommend Different
Reagent and DNA Amounts

Recommended Starting Conditions
(per well of a 6-well plate)

Final Reagent to DNA
Ratio (µl:µg)
3:1 1.5:1 6:1
 
TransIT-LT1 Reagent 7.5 µl    
DNA 2.5 µg    
 
FuGENE 6 Reagent 3 µl 3 µl 6 µl
DNA 1 µg 2 µg 1 µg

 

2.5X More DNA and Reagent Results in up to 12X More Gene Expression

Figure 1

The indicated cell lines were transfected in duplicate with the recommended amounts of transfection reagent and luciferase expression vector (per 12-well) from the TransIT-LT1 and FuGENE 6 protocols to achieve a final 3:1 ratio. Cells were harvested 24 hours post-transfection and assayed for luciferase activity.

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